Defective phagocyte Aspergillus killing associated with recurrent pulmonary aspergillus infections

A. Fietta, F. Sacchi, P. Mangiarotti, G. Manara, G. Gialdroni Grassi

Research output: Contribution to journalArticle

Abstract

An apparently healthy boy was suffering from recurrent Aspergillus infections. No classical conditions of immunodeficiency were found. Studies on the patient's phagocytic system revealed neutrophils and monocytes to function normally except in Aspergillus killing (microbicidal activity for bacteria and Candida was normal). Aspergillus killing mechanisms may be complex and peculiarly selective, possibly involving both oxygen-dependent and independent mechanisms.

Original languageEnglish
Pages (from-to)10-13
Number of pages4
JournalInfection
Volume12
Issue number1
DOIs
Publication statusPublished - Jan 1984

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

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