Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances

Ralf Veit, Lilian Konicar, Jens G. Klinzing, Beatrix Barth, Özge Yilmaz, Niels Birbaumer

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The diminished fear reactivity is one of the most valid physiological findings in psychopathy research. In a fear conditioning paradigm, with faces as conditioned stimulus (CS) and electric shock as unconditioned stimulus (US), we investigated a sample of 14 high psychopathic violent offenders. Event related potentials, skin conductance responses (SCR) as well as subjective ratings of the CSs were collected. This study assessed to which extent the different facets of the psychopathy construct contribute to the fear conditioning deficits observed in psychopaths. Participants with high scores on the affective facet subscale of the Psychopathy Checklist-Revised (PCL-R) showed weaker conditioned fear responses and lower N100 amplitudes compared to low scorers. In contrast, high scorers on the affective facet rated the CS+ (paired) more negatively than low scorers regarding the CS- (unpaired). Regarding the P300, high scores on the interpersonal facet were associated with increased amplitudes to the CS+ compared to the CS-, while the opposed pattern was found for the antisocial facet. Both, the initial and terminal contingent negative variation indicated a divergent pattern: participants with pronounced interpersonal deficits, showed increased cortical negativity to the CS+ compared to the CS-, whereas a reversed CS+/CS- differentiation was found in offenders scoring high on the antisocial facet. The present study revealed that deficient fear conditioning in psychopathy was most pronounced in offenders with high scores on the affective facet. Event related potentials suggest that participants with distinct interpersonal deficits showed increased information processing, whereas the antisocial facet was linked to decreased attention and interest to the CS+. These data indicate that an approach to the facets of psychopathy can help to resolve ambiguous findings in psychopathy research and enables a more precise and useful description of this disorder.

Original languageEnglish
Article number706
JournalFrontiers in Human Neuroscience
Issue numberOCT
DOIs
Publication statusPublished - Oct 25 2013

Fingerprint

Fear
Evoked Potentials
Contingent Negative Variation
Checklist
Automatic Data Processing
Research
Shock
Conditioning (Psychology)
Skin

Keywords

  • Electrophysiology
  • Emotional-cognitive interaction
  • Fear conditioning
  • Psychopathy
  • Skin conductance

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology
  • Psychiatry and Mental health
  • Neurology
  • Biological Psychiatry

Cite this

Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances. / Veit, Ralf; Konicar, Lilian; Klinzing, Jens G.; Barth, Beatrix; Yilmaz, Özge; Birbaumer, Niels.

In: Frontiers in Human Neuroscience, No. OCT, 706, 25.10.2013.

Research output: Contribution to journalArticle

Veit, Ralf ; Konicar, Lilian ; Klinzing, Jens G. ; Barth, Beatrix ; Yilmaz, Özge ; Birbaumer, Niels. / Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances. In: Frontiers in Human Neuroscience. 2013 ; No. OCT.
@article{d04669196a9940cba5e90e5aaf3fcffe,
title = "Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances",
abstract = "The diminished fear reactivity is one of the most valid physiological findings in psychopathy research. In a fear conditioning paradigm, with faces as conditioned stimulus (CS) and electric shock as unconditioned stimulus (US), we investigated a sample of 14 high psychopathic violent offenders. Event related potentials, skin conductance responses (SCR) as well as subjective ratings of the CSs were collected. This study assessed to which extent the different facets of the psychopathy construct contribute to the fear conditioning deficits observed in psychopaths. Participants with high scores on the affective facet subscale of the Psychopathy Checklist-Revised (PCL-R) showed weaker conditioned fear responses and lower N100 amplitudes compared to low scorers. In contrast, high scorers on the affective facet rated the CS+ (paired) more negatively than low scorers regarding the CS- (unpaired). Regarding the P300, high scores on the interpersonal facet were associated with increased amplitudes to the CS+ compared to the CS-, while the opposed pattern was found for the antisocial facet. Both, the initial and terminal contingent negative variation indicated a divergent pattern: participants with pronounced interpersonal deficits, showed increased cortical negativity to the CS+ compared to the CS-, whereas a reversed CS+/CS- differentiation was found in offenders scoring high on the antisocial facet. The present study revealed that deficient fear conditioning in psychopathy was most pronounced in offenders with high scores on the affective facet. Event related potentials suggest that participants with distinct interpersonal deficits showed increased information processing, whereas the antisocial facet was linked to decreased attention and interest to the CS+. These data indicate that an approach to the facets of psychopathy can help to resolve ambiguous findings in psychopathy research and enables a more precise and useful description of this disorder.",
keywords = "Electrophysiology, Emotional-cognitive interaction, Fear conditioning, Psychopathy, Skin conductance",
author = "Ralf Veit and Lilian Konicar and Klinzing, {Jens G.} and Beatrix Barth and {\"O}zge Yilmaz and Niels Birbaumer",
year = "2013",
month = "10",
day = "25",
doi = "10.3389/fnhum.2013.00706",
language = "English",
journal = "Frontiers in Human Neuroscience",
issn = "1662-5161",
publisher = "Frontiers Media S. A.",
number = "OCT",

}

TY - JOUR

T1 - Deficient fear conditioning in psychopathy as a function of interpersonal and affective disturbances

AU - Veit, Ralf

AU - Konicar, Lilian

AU - Klinzing, Jens G.

AU - Barth, Beatrix

AU - Yilmaz, Özge

AU - Birbaumer, Niels

PY - 2013/10/25

Y1 - 2013/10/25

N2 - The diminished fear reactivity is one of the most valid physiological findings in psychopathy research. In a fear conditioning paradigm, with faces as conditioned stimulus (CS) and electric shock as unconditioned stimulus (US), we investigated a sample of 14 high psychopathic violent offenders. Event related potentials, skin conductance responses (SCR) as well as subjective ratings of the CSs were collected. This study assessed to which extent the different facets of the psychopathy construct contribute to the fear conditioning deficits observed in psychopaths. Participants with high scores on the affective facet subscale of the Psychopathy Checklist-Revised (PCL-R) showed weaker conditioned fear responses and lower N100 amplitudes compared to low scorers. In contrast, high scorers on the affective facet rated the CS+ (paired) more negatively than low scorers regarding the CS- (unpaired). Regarding the P300, high scores on the interpersonal facet were associated with increased amplitudes to the CS+ compared to the CS-, while the opposed pattern was found for the antisocial facet. Both, the initial and terminal contingent negative variation indicated a divergent pattern: participants with pronounced interpersonal deficits, showed increased cortical negativity to the CS+ compared to the CS-, whereas a reversed CS+/CS- differentiation was found in offenders scoring high on the antisocial facet. The present study revealed that deficient fear conditioning in psychopathy was most pronounced in offenders with high scores on the affective facet. Event related potentials suggest that participants with distinct interpersonal deficits showed increased information processing, whereas the antisocial facet was linked to decreased attention and interest to the CS+. These data indicate that an approach to the facets of psychopathy can help to resolve ambiguous findings in psychopathy research and enables a more precise and useful description of this disorder.

AB - The diminished fear reactivity is one of the most valid physiological findings in psychopathy research. In a fear conditioning paradigm, with faces as conditioned stimulus (CS) and electric shock as unconditioned stimulus (US), we investigated a sample of 14 high psychopathic violent offenders. Event related potentials, skin conductance responses (SCR) as well as subjective ratings of the CSs were collected. This study assessed to which extent the different facets of the psychopathy construct contribute to the fear conditioning deficits observed in psychopaths. Participants with high scores on the affective facet subscale of the Psychopathy Checklist-Revised (PCL-R) showed weaker conditioned fear responses and lower N100 amplitudes compared to low scorers. In contrast, high scorers on the affective facet rated the CS+ (paired) more negatively than low scorers regarding the CS- (unpaired). Regarding the P300, high scores on the interpersonal facet were associated with increased amplitudes to the CS+ compared to the CS-, while the opposed pattern was found for the antisocial facet. Both, the initial and terminal contingent negative variation indicated a divergent pattern: participants with pronounced interpersonal deficits, showed increased cortical negativity to the CS+ compared to the CS-, whereas a reversed CS+/CS- differentiation was found in offenders scoring high on the antisocial facet. The present study revealed that deficient fear conditioning in psychopathy was most pronounced in offenders with high scores on the affective facet. Event related potentials suggest that participants with distinct interpersonal deficits showed increased information processing, whereas the antisocial facet was linked to decreased attention and interest to the CS+. These data indicate that an approach to the facets of psychopathy can help to resolve ambiguous findings in psychopathy research and enables a more precise and useful description of this disorder.

KW - Electrophysiology

KW - Emotional-cognitive interaction

KW - Fear conditioning

KW - Psychopathy

KW - Skin conductance

UR - http://www.scopus.com/inward/record.url?scp=84887957133&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887957133&partnerID=8YFLogxK

U2 - 10.3389/fnhum.2013.00706

DO - 10.3389/fnhum.2013.00706

M3 - Article

AN - SCOPUS:84887957133

JO - Frontiers in Human Neuroscience

JF - Frontiers in Human Neuroscience

SN - 1662-5161

IS - OCT

M1 - 706

ER -