Defining and classifying cancer cachexia: A proposal by the SCRINIO Working Group

Federico Bozzetti, Luigi Mariani

Research output: Contribution to journalArticlepeer-review


Background: Although cancer cachexia is widely diffuse in the cancer patient population, there is no objective definition and classification of this syndrome. The purpose of this study is to propose a simple and quick classification that relies on the severity of the body weight loss and presence/absence of symptoms that are associated with cancer cachexia. Methods: The authors used a database of an ongoing multicenter prospective investigation on the screening of the nutrition risk of 1307 cancer outpatients from different (mainly Italian) university or scientific institutes or hospitals. The database included demographic, oncologic, clinical, and nutrition data. The patients were divided into 4 classes based on combinations of body weight loss (

Original languageEnglish
Pages (from-to)361-367
Number of pages7
JournalJournal of Parenteral and Enteral Nutrition
Issue number4
Publication statusPublished - Jul 2009


  • Anorexia
  • Cachexia classification
  • Cachexia staging
  • Cancer cachexia
  • Early satiation
  • Fatigue
  • Weight loss

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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