Delayed graft function and chronic allograft nephropathy: diagnostic and prognostic role of neutrophil gelatinase-associated lipocalin

Antonio Lacquaniti, Chiara Caccamo, Paola Salis, Valeria Chirico, Antoine Buemi, Valeria Cernaro, Alberto Noto, Giuseppina Pettinato, Domenico Santoro, Tullio Bertani, Michele Buemi, Antonio David

Research output: Contribution to journalArticlepeer-review

Abstract

Context: Available markers are not reliable parameters to early detect kidney injury in transplanted patients. Objective: Examine neutrophil gelatinase associated lipocalin (NGAL) in early detection of delayed graft function (DGF) and as a long-term predictor of graft outcome. Patients and methods: NGAL was evaluated in 124 transplanted patients. Results: Urinary NGAL levels were associated to a 10% (HR: 1.10; 95% CI: 1.04–1.25; p 

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalBiomarkers
DOIs
Publication statusPublished - Feb 2016

Keywords

  • Biomarker
  • chronic allograft nephropathy
  • delayed graft function
  • kidney transplantation
  • long-term graft failure
  • neutrophil gelatinase associated lipocalin

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Health, Toxicology and Mutagenesis

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