Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: A case-control study

P. Vineis, L. Miligi, P. Crosignani, L. Davico, A. Fontana, G. Masala, O. Nanni, V. Ramazzotti, S. Rodella, E. Stagnaro, R. Tumino, C. Viganò, C. Vindigni, A. S. Costantini

Research output: Contribution to journalArticle

Abstract

In a population-based case-control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1-16.2). We propose that late infection is a proliferative stimulus for B-cells.

Original languageEnglish
Pages (from-to)47-49
Number of pages3
JournalBritish Journal of Cancer
Volume88
Issue number1
DOIs
Publication statusPublished - Jan 13 2003

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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    Vineis, P., Miligi, L., Crosignani, P., Davico, L., Fontana, A., Masala, G., Nanni, O., Ramazzotti, V., Rodella, S., Stagnaro, E., Tumino, R., Viganò, C., Vindigni, C., & Costantini, A. S. (2003). Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia: A case-control study. British Journal of Cancer, 88(1), 47-49. https://doi.org/10.1038/sj.bjc.6600689