Delaying surgery for patients with a previous SARS-CoV-2 infection

COVIDSurg Collaborative, Simone Ferrero, Piero Fregatti, Stefano Scabini

Research output: Contribution to journalArticlepeer-review


EditorWith at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.The COVIDSurg-Cancer study was a prospective cohort study of patients undergoing curative elective cancer surgery during the COVID-19 pandemic up to 24 May 20203. We performed a pre-planned subgroup analysis of patients undergoing surgery with previous SARS-CoV-2 positive swab that were not suspected to have active COVID-19 at the time of surgery. Propensity score matching was used to match previous SARS-CoV-2 swab positive patients to patients with no a positive swab test in a 1:4 ratio. Multivariable logistic regression was used to explore associations of previous SARS-CoV-2 with rates of postoperative pulmonary complications and death in matched groups. Full methodology is available in the Appendix.
Original languageUndefined/Unknown
Pages (from-to)e601-e602
JournalAnn. Surg.
Issue number12
Publication statusPublished - Sep 1 2020

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