Deletions of 17p and p53 mutations in preneoplastic lesions of the lung

G. Sozzi, M. Miozzo, R. Donghi, S. Pilotti, C. T. Cariani, U. Pastorino, G. Della Porta, M. A. Pierotti

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Abstract

Cytogenetic and p53 mutation analysis in two cases of severe dysplasia of the bronchial epithelium in lung cancer patients and p53 immunostaining in a third one are reported. The finding of both chromosomal deletions of 17p and p53 mutation indicates that these changes may take place early in the process of lung carcinogenesis.

Original languageEnglish
Pages (from-to)6079-6082
Number of pages4
JournalCancer Research
Volume52
Issue number21
Publication statusPublished - 1992

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Lung
Mutation
Cytogenetics
Lung Neoplasms
Carcinogenesis
Epithelium

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Sozzi, G., Miozzo, M., Donghi, R., Pilotti, S., Cariani, C. T., Pastorino, U., ... Pierotti, M. A. (1992). Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. Cancer Research, 52(21), 6079-6082.

Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. / Sozzi, G.; Miozzo, M.; Donghi, R.; Pilotti, S.; Cariani, C. T.; Pastorino, U.; Della Porta, G.; Pierotti, M. A.

In: Cancer Research, Vol. 52, No. 21, 1992, p. 6079-6082.

Research output: Contribution to journalArticle

Sozzi, G, Miozzo, M, Donghi, R, Pilotti, S, Cariani, CT, Pastorino, U, Della Porta, G & Pierotti, MA 1992, 'Deletions of 17p and p53 mutations in preneoplastic lesions of the lung', Cancer Research, vol. 52, no. 21, pp. 6079-6082.
Sozzi G, Miozzo M, Donghi R, Pilotti S, Cariani CT, Pastorino U et al. Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. Cancer Research. 1992;52(21):6079-6082.
Sozzi, G. ; Miozzo, M. ; Donghi, R. ; Pilotti, S. ; Cariani, C. T. ; Pastorino, U. ; Della Porta, G. ; Pierotti, M. A. / Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. In: Cancer Research. 1992 ; Vol. 52, No. 21. pp. 6079-6082.
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