Delivery of radiofrequency energy to the gastroesophageal junction (Stretta procedure) for the treatment of gastroesophageal reflux disease

L. Cipolletta, G. Rotondano, L. Dughera, A. Repici, M. A. Bianco, C. De Angelis, A. M. Vingiani, E. Battaglia

Research output: Contribution to journalArticle

Abstract

Background: Radiofrequency (RF) energy treatment is increasingly offered before invasive surgical procedures for selected patients with gastroesophageal reflux disease (GERD). Methods: Thirty-two patients undergoing the Stretta procedure were prospectively evaluated with upper endoscopy, manometry, 24-hour pH testing, SF-36 surveys, and GERD-specific questionnaires (GERD HRQL). Results: Significant clinical improvement was observed in 91% of patients (29/32). Mean heartburn and GERD HRQL scores decreased (p = 0.001 and p = 0.003, respectively), and physical SF-36 increased (p = 0.05). At a minimum follow-up of 12 months, median esophageal acid exposure decreased (p = 0.79) and was normalized in eight patients. Median lower esophageal sphincter (LES) pressure was unchanged. Esophagitis healed in six of eight patients, but two patients with nonerosive disease developed asymptomatic grade A esophagitis during follow-up. At 12 months, 56% of patients were off proton pump inhibits. Morbidity was minimal. Conclusions: RF delivery to LES is safe and significantly improves symptoms and quality of life in selected GERD patients.

Original languageEnglish
Pages (from-to)849-853
Number of pages5
JournalSurgical Endoscopy and Other Interventional Techniques
Volume19
Issue number6
DOIs
Publication statusPublished - Jun 2005

Keywords

  • Endoscopic therapy
  • Gastroesophageal reflux disease
  • Quality of life
  • Radiofrequency delivery
  • Symptoms

ASJC Scopus subject areas

  • Surgery

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