With the aim to assess difficulties and problems which can prevent the achievement of a good metabolic control in insulin-treated patients, a multicentre study has been undertaken in order to obtain information about demographic, clinical and treatment features of these patients in Italy. 20 outpatient diabetes clinics, randomly selected all over the country, gave the complete list of insulin-treated patients they had in charge from January to June 1993. Among them 200 patients for each clinic have been randomly identified and data obtained from their clinical records. Out of 3525 patients, 646 were classified as having IDDM, 2720 NIDDM and 159 couldn't be classified. IDDM patients were mostly males, while females were strongly prevalent among NIDDM, especially in the elderly. Overweight or obesity was observed in 70% of NIDDM; IDDM had more intensive clinical care and a better metabolic control (HbA(1c)) than NIDDM. Metabolic control well correlated with body mass index, clinical care, daily insulin injections, occupational and cultural status. The most frequent insulin regimen was the one with 2 injections/day in NIDDM and the one with 3 injections in IDDM; up to 50% of NIDDM were also treated with oral hypoglycemic agents. 40% of IDDM used a pen injector at least once-a-day, but this was rarely used by NIDDM. The most employed intermediate-acting insulin was NPH and common was the use of premixed insulins. The most frequent ratio in insulin mixtures was 30:70, but 50:50 (at lunch) and 20:80 (at breakfast) were also used. These results demonstrate the feasibility of a multicentre study concerning the features of insulin-treated diabetic patients in Italy and indicate some approaches (clinical care, education, nutrition, therapy) which could improve their metabolic control, often unsatisfactory.
|Number of pages||7|
|Journal||Giornale Italiano di Diabetologia|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Internal Medicine