Demyelination and cortical reorganization: Functional MRI data from a case of subacute combined degeneration

Research output: Contribution to journalArticle


Although it is accepted that functional changes of the cortex can occur in patients with white matter diseases of the brain and might have an adaptive role in limiting the clinical consequences of subcortical injury, the pathological substrates able to elicit such cortical changes are still unknown. This multiparametric magnetic resonance study of a patient with an early diagnosis of subacute combined degeneration suggests that demyelination alone does not necessarily induce adaptive functional changes of the cerebral cortex.

Original languageEnglish
Pages (from-to)558-563
Number of pages6
Issue number2
Publication statusPublished - Feb 1 2003


ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

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