Dendritic cell differentiation from hematopoietic CD34+ progenitor cells

A. Curti, M. Fogli, M. Ratta, G. Biasco, S. Tura, R. M. Lemoli

Research output: Contribution to journalArticle

Abstract

Dendritic cells (DC) are the most powerful antigen presenting cells (APC) and play a pivotal role in initiating the immune response. In light of their unique properties, DC have been proposed as a tool to enhance immunity against infectious agents and in anticancer vaccine strategies. In the last few years, the development of DC has been extensively investigated. The present paper summarizes the most recent findings on the differentiation of myeloid DC from hematopoietic CD34+ progenitors and methods for DC generation in vitro. A better understanding of DC function has important implications for their use in clinical settings.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalJournal of Biological Regulators and Homeostatic Agents
Volume15
Issue number1
Publication statusPublished - 2001

Keywords

  • Cellular differentiation
  • Cytokines
  • Dendritic cells
  • Hematopoiesis

ASJC Scopus subject areas

  • Immunology
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Physiology (medical)
  • Medicine (miscellaneous)
  • Physiology
  • Agricultural and Biological Sciences(all)

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