Dendritic cell differentiation from hematopoietic CD34+ progenitor cells

A. Curti, M. Fogli, M. Ratta, G. Biasco, S. Tura, R. M. Lemoli

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Dendritic cells (DC) are the most powerful antigen presenting cells (APC) and play a pivotal role in initiating the immune response. In light of their unique properties, DC have been proposed as a tool to enhance immunity against infectious agents and in anticancer vaccine strategies. In the last few years, the development of DC has been extensively investigated. The present paper summarizes the most recent findings on the differentiation of myeloid DC from hematopoietic CD34+ progenitors and methods for DC generation in vitro. A better understanding of DC function has important implications for their use in clinical settings.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalJournal of Biological Regulators and Homeostatic Agents
Volume15
Issue number1
Publication statusPublished - 2001

Fingerprint

dendritic cells
Hematopoietic Stem Cells
cell differentiation
Dendritic Cells
Cell Differentiation
antigen-presenting cells
Antigen-Presenting Cells
Myeloid Cells
Antineoplastic Agents
hematopoietic stem cells
Immunity
Vaccines
immunity
immune response
vaccines
pathogens

Keywords

  • Cellular differentiation
  • Cytokines
  • Dendritic cells
  • Hematopoiesis

ASJC Scopus subject areas

  • Immunology
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Physiology (medical)
  • Medicine (miscellaneous)
  • Physiology
  • Agricultural and Biological Sciences(all)

Cite this

Dendritic cell differentiation from hematopoietic CD34+ progenitor cells. / Curti, A.; Fogli, M.; Ratta, M.; Biasco, G.; Tura, S.; Lemoli, R. M.

In: Journal of Biological Regulators and Homeostatic Agents, Vol. 15, No. 1, 2001, p. 49-52.

Research output: Contribution to journalArticle

Curti, A. ; Fogli, M. ; Ratta, M. ; Biasco, G. ; Tura, S. ; Lemoli, R. M. / Dendritic cell differentiation from hematopoietic CD34+ progenitor cells. In: Journal of Biological Regulators and Homeostatic Agents. 2001 ; Vol. 15, No. 1. pp. 49-52.
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