Dendritic cells and the complexity of microbial infection

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Dendritic cells (DCs) can discriminate between different classes of microorganisms, present antigens to T cells and initiate innate and adaptive immune responses. DCs do not act individually, and their function can be fine-tuned by environmental and tissue factors as well as by the microorganisms themselves. Recent studies have reported DCs can integrate stimuli derived from microbial pathogens and other cells present at, or recruited to, the site of infection. These interactions can determine the success or failure of the immune response induced against pathogens.

Original languageEnglish
Pages (from-to)426-431
Number of pages6
JournalTrends in Microbiology
Volume10
Issue number9
Publication statusPublished - Sep 1 2002

Fingerprint

Dendritic Cells
Infection
Thromboplastin
Adaptive Immunity
Innate Immunity
T-Lymphocytes
Antigens

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Cite this

Dendritic cells and the complexity of microbial infection. / Rescigno, Maria.

In: Trends in Microbiology, Vol. 10, No. 9, 01.09.2002, p. 426-431.

Research output: Contribution to journalArticle

@article{ce242cd8c19742a4bcdba21602f2b06f,
title = "Dendritic cells and the complexity of microbial infection",
abstract = "Dendritic cells (DCs) can discriminate between different classes of microorganisms, present antigens to T cells and initiate innate and adaptive immune responses. DCs do not act individually, and their function can be fine-tuned by environmental and tissue factors as well as by the microorganisms themselves. Recent studies have reported DCs can integrate stimuli derived from microbial pathogens and other cells present at, or recruited to, the site of infection. These interactions can determine the success or failure of the immune response induced against pathogens.",
author = "Maria Rescigno",
year = "2002",
month = "9",
day = "1",
language = "English",
volume = "10",
pages = "426--431",
journal = "Trends in Microbiology",
issn = "0966-842X",
publisher = "Elsevier Limited",
number = "9",

}

TY - JOUR

T1 - Dendritic cells and the complexity of microbial infection

AU - Rescigno, Maria

PY - 2002/9/1

Y1 - 2002/9/1

N2 - Dendritic cells (DCs) can discriminate between different classes of microorganisms, present antigens to T cells and initiate innate and adaptive immune responses. DCs do not act individually, and their function can be fine-tuned by environmental and tissue factors as well as by the microorganisms themselves. Recent studies have reported DCs can integrate stimuli derived from microbial pathogens and other cells present at, or recruited to, the site of infection. These interactions can determine the success or failure of the immune response induced against pathogens.

AB - Dendritic cells (DCs) can discriminate between different classes of microorganisms, present antigens to T cells and initiate innate and adaptive immune responses. DCs do not act individually, and their function can be fine-tuned by environmental and tissue factors as well as by the microorganisms themselves. Recent studies have reported DCs can integrate stimuli derived from microbial pathogens and other cells present at, or recruited to, the site of infection. These interactions can determine the success or failure of the immune response induced against pathogens.

UR - http://www.scopus.com/inward/record.url?scp=0036710649&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036710649&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0036710649

VL - 10

SP - 426

EP - 431

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

IS - 9

ER -