Originalarbeit: Depression und lebensqualität bei patienten mit amyotropher lateralsklerose

Translated title of the contribution: Depression and quality of life in patients with amyotrophic lateral sclerosis

Dorothée Lulé, Sonja Häcker, Albert Ludolph, Niels Birbaumer, Andrea Kübler

Research output: Contribution to journalArticle

Abstract

Introduction: There is increasing debate on the issue of whether to facilitate the end-of-life decisions of severely disabled paients with diseases such as amyotrophic lateral sclerosis (ALS). Our two studies were intended to explore the emotional state and quality of life of patients with ALS. Methods: Two studies were performed to investigate depression and the quality of life in ALS patients: one was a longitudinal study, the other a comparison of ALS patients to normal control subjects. Results: These studies found no correlation between physical disability in ALS and either depression or the quality of life. The rate of depression was found to be inversely related to educational status. A satisfactory quality of life without depressive manifestations seems to be possible in any stage of ALS. In ALS patients the quality of life was comparable with healthy controls. Discussion: The rationale for not providing life-sustaining treatment to severely disabled patients is that a poor quality of life is expected after such treatment. Our studies have shown, however, that ALS patients can experience a satisfactory quality of life even if they are severely physically impaired, including in the terminal phase.

Translated title of the contributionDepression and quality of life in patients with amyotrophic lateral sclerosis
Original languageGerman
Pages (from-to)397-403
Number of pages7
JournalDeutsches Arzteblatt
Volume105
Issue number23
DOIs
Publication statusPublished - Jun 6 2008

Keywords

  • Amyotrophic lateral sclerosis
  • Assisted suicide
  • Depression
  • Quality of life
  • Respiratory insufficiency

ASJC Scopus subject areas

  • Medicine(all)

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