Depression circumstantially related to the administration of finasteride for androgenetic alopecia

Gianfranco Altomare, Giovanni Luigi Capella

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

In this paper we report 19 patients (14 males, 5 females; mean age 28.16 years ± 7.68 SD) out of a series of 23 (17 males, 5 females) who developed a mood disturbance (moderate to severe depression) during treatment with finasteride, 1 mg/day orally, for androgenetic alopecia (Hamilton subtypes III-V; Ludwig subtypes I-II). Depression, which significatively impaired sociofamilial relations, sleep and eating behaviour, was associated to marked anxiety in some cases, developed after 9-19 weeks of treatment with finasteride, and promptly resolved after suspension of the drug. Two patients accepted reintroduction of the drug, and depression relapsed within 2 weeks. Depression as an adverse effect of finasteride has been reported only once. Further studies are needed to confirm our circumstantial observations, which are based on a retrospective series of patients.

Original languageEnglish
Pages (from-to)665-669
Number of pages5
JournalJournal of Dermatology
Volume29
Issue number10
Publication statusPublished - Oct 1 2002

Fingerprint

Finasteride
Alopecia
Depression
Feeding Behavior
Pharmaceutical Preparations
Suspensions
Sleep
Anxiety
Therapeutics

Keywords

  • Alopecia
  • Depression
  • Drug reaction
  • Finasteride
  • Mood disorder

ASJC Scopus subject areas

  • Dermatology

Cite this

Depression circumstantially related to the administration of finasteride for androgenetic alopecia. / Altomare, Gianfranco; Capella, Giovanni Luigi.

In: Journal of Dermatology, Vol. 29, No. 10, 01.10.2002, p. 665-669.

Research output: Contribution to journalArticle

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