Depression, obesity and their comorbidity during pregnancy: effects on the offspring’s mental and physical health

Nadia Cattane, Katri Räikkönen, Roberta Anniverno, Claudio Mencacci, Marco A. Riva, Carmine M. Pariante, Annamaria Cattaneo

Research output: Contribution to journalReview articlepeer-review

Abstract

Depression and obesity represent two of the most common complications during pregnancy and are associated with severe health risks for both the mother and the child. Although several studies have analysed the individual effects of depression or obesity on the mothers and their children, the effects associated with the co-occurrence of both disorders have so far been poorly investigated. The relationship between depression and obesity is very complex and it is still unclear whether maternal depression leads to obesity or vice versa. It is well known that the intrauterine environment plays an important role in mediating the effects of both depression and obesity in the mother on the fetal programming, increasing the child’s risk to develop negative outcomes.

Original languageEnglish
Pages (from-to)462-481
JournalMolecular Psychiatry
DOIs
Publication statusPublished - 2020

Keywords

  • Depression
  • Mental health
  • Physical health

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

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