Depressive, negative and positive symptoms in schizophrenia: Response to different dosages of haloperidol

M. C. Mauri, V. Laini, C. P C Steinhilber, L. Boscati

Research output: Contribution to journalArticle

Abstract

81 chronic schizophrenic in-patients during a riexacerbation phase, were included into the study. The patients were treated with HL from 1.50 to 18.00 mg p.o., t.i.d. No significant correlations were found among HRSD, SANS and SAPS. All the patients showed a significant amelioration at BPRS, HRSD, SAPS and SANS at the HL dosage below 0.2 mg/kg (<8.5 mg/die), while at the dosage up to 0.2 mg/kg (≤ 14.8 mg/die), they showed an amelioration only at BPRS and SAPS. Upper dosages of HL seem to show their efficacy on productive symptoms, while the efficacy on negative and depressive symptoms appeared only at lower dosages.

Original languageEnglish
Pages (from-to)59-63
Number of pages5
JournalNew Trends in Experimental and Clinical Psychiatry
Volume14
Issue number1
Publication statusPublished - 1998

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Keywords

  • Depressive
  • Haloperidol dosages
  • Negative-positive symptoms
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health

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