Dermoscopic features of squamous cell carcinoma on the lips

E. Benati, F. Persechino, S Piana, G. Argenziano, Aimilios Lallas, E Moscarella, F Castagnetti, C Longo

Research output: Contribution to journalArticlepeer-review


BACKGROUND: Dermoscopy of cutaneous squamous cell carcinoma (SCC) has already been described. However little is known on the dermoscopic features of lip SCC.

OBJECTIVES: to describe the clinic and dermoscopic criteria of lip SCC, METHODS: Clinical and dermoscopic images of lip SCC were retrospectively evaluated for the presence of specific dermoscopic criteria. Cases were collected from Skin Cancer Unit of Reggio Emilia, Italy, Dermatology Unit Second University of Naples, Italy, and First Department of Dermatology of Aristotle University of Thessaloniki, Greece.

RESULTS: We collected 22 lip SCC; the majority were located on the lower lip (90.9%); more than 2/3 of the total series were flat (68.2%). The clinical images revealed that white-yellowish and red colours were almost equally presented and usually combined together. The predominant clinical aspect that characterized lip SCC was the presence of ulceration (90.9%). Dermoscopically, we noticed polymorphous unfocused small size vessels located both peripheral or throughout the lesions. Scales and white structures were observed in all lesions.

CONCLUSIONS: The presence of ulceration, scales, polymorphous vessels and white structures are the main dermoscopic features of lip SCC. This article is protected by copyright. All rights reserved.

Original languageEnglish
JournalBritish Journal of Dermatology
Publication statusE-pub ahead of print - Dec 23 2016


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