TY - JOUR
T1 - Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity
AU - Longo, Caterina
AU - Zalaudek, Iris
AU - Piana, Simonetta
AU - Pellacani, Giovanni
AU - Lallas, Aimilios
AU - Reggiani, Camilla
AU - Argenziano, Giuseppe
PY - 2013/8
Y1 - 2013/8
N2 - IMPORTANCE Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially. OBSERVATIONS In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a "clod" pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features. CONCLUSIONS AND RELEVANCE Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.
AB - IMPORTANCE Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially. OBSERVATIONS In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a "clod" pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features. CONCLUSIONS AND RELEVANCE Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.
UR - http://www.scopus.com/inward/record.url?scp=84883197220&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883197220&partnerID=8YFLogxK
U2 - 10.1001/jamadermatol.2013.321
DO - 10.1001/jamadermatol.2013.321
M3 - Article
C2 - 23740161
AN - SCOPUS:84883197220
VL - 149
SP - 941
EP - 945
JO - JAMA Dermatology
JF - JAMA Dermatology
SN - 2168-6068
IS - 8
ER -