Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity

Caterina Longo, Iris Zalaudek, Simonetta Piana, Giovanni Pellacani, Aimilios Lallas, Camilla Reggiani, Giuseppe Argenziano

Research output: Contribution to journalArticle

Abstract

IMPORTANCE Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially. OBSERVATIONS In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a "clod" pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features. CONCLUSIONS AND RELEVANCE Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.

Original languageEnglish
Pages (from-to)941-945
Number of pages5
JournalJAMA Dermatology
Volume149
Issue number8
DOIs
Publication statusPublished - Aug 2013

ASJC Scopus subject areas

  • Dermatology

Fingerprint Dive into the research topics of 'Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity'. Together they form a unique fingerprint.

  • Cite this