TY - JOUR
T1 - Dermoscopy and reflectance confocal microscopy for monitoring the treatment of actinic cheilitis with ingenol mebutate gel
T2 - Report of three cases
AU - Benati, E.
AU - Pampena, R.
AU - Bombonato, C.
AU - Borsari, S.
AU - Lombardi, M.
AU - Longo, C.
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Actinic cheilitis (AC) can precede the development of squamous cell carcinoma (SCC) of the lip, a location with higher risk of invasiveness and metastasis. Herein, we reported the use of ingenol mebutate (IngMeb) 0.015% gel on three consecutive days to treat three patients suffering from AC. All the three patients achieved complete clearance of AC with rapid clinical effect, favorable safety profile, good patient's compliance related to short time of applications, and few local skin reactions. So IngMeb is an attractive new therapy for AC. Moreover, the present case report adds further evidence to the usefulness of dermoscopy and Reflectance confocal microscopy (RCM) in the assessment and monitoring of treatment outcome.
AB - Actinic cheilitis (AC) can precede the development of squamous cell carcinoma (SCC) of the lip, a location with higher risk of invasiveness and metastasis. Herein, we reported the use of ingenol mebutate (IngMeb) 0.015% gel on three consecutive days to treat three patients suffering from AC. All the three patients achieved complete clearance of AC with rapid clinical effect, favorable safety profile, good patient's compliance related to short time of applications, and few local skin reactions. So IngMeb is an attractive new therapy for AC. Moreover, the present case report adds further evidence to the usefulness of dermoscopy and Reflectance confocal microscopy (RCM) in the assessment and monitoring of treatment outcome.
KW - actinic cheilitis
KW - ingenol mebutate
KW - reflectance confocal microscopy
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U2 - 10.1111/dth.12613
DO - 10.1111/dth.12613
M3 - Article
AN - SCOPUS:85045846986
VL - 31
JO - Dermatologic Therapy
JF - Dermatologic Therapy
SN - 1396-0296
IS - 4
M1 - e12613
ER -