Dermoscopy of pigmented lesions of the vulva: A retrospective morphological study

Angela Ferrari, Iris Zalaudek, Giuseppe Argenziano, Pierluigi Buccini, Paola De Simone, Vitaliano Silipo, Laura Eibenschutz, Giustino Mariani, Renato Covello, Isabella Sperduti, Luciano Mariani, Caterina Catricalà

Research output: Contribution to journalArticlepeer-review


Background: The dermoscopic patterns of pigmented skin tumors are influenced by the body site. Objective: To evaluate the clinical and dermoscopic features associated with pigmented vulvar lesions. Methods: Retrospective analysis of clinical and dermoscopic images of vulvar lesions. The χ2 test was used to test the association between clinical data and histopathological diagnosis. Results: A total of 42 (32.8%) melanocytic and 86 (67.2%) nonmelanocytic vulvar lesions were analyzed. Nevi significantly prevailed in younger women compared with melanomas and melanosis and exhibited most commonly a globular/cobblestone (51.3%) and a mixed (21.6%) pattern. Dermoscopically all melanomas showed a multicomponent pattern. Melanotic macules showed clinical overlapping features with melanoma, but their dermoscopic patterns differed significantly from those observed in melanomas. Conclusion: The diagnosis and management of pigmented vulvar lesions should be based on a good clinicodermoscopic correlation. Dermoscopy may be helpful in the differentiation of solitary melanotic macules from early melanoma.

Original languageEnglish
Pages (from-to)157-166
Number of pages10
Issue number2
Publication statusPublished - May 2011


  • Dermoscopy
  • Melanoma, genital
  • Nevus
  • Vulva

ASJC Scopus subject areas

  • Dermatology


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