Abstract
Background Naevus sebaceous is a congenital hamartoma commonly associated with the development of secondary neoplasms. There are sparse data relating to the dermoscopy of tumours arising in naevus sebaceous. Objectives To evaluate the dermoscopic features of a large series of neoplasms arising in naevus sebaceous. Methods Digital dermoscopic images of 58 histopathologically confirmed cases of secondary neoplasms arising in naevus sebaceous collected from 11 hospitals in Spain, France, Italy and Austria were evaluated for the presence of dermoscopic structures and patterns. Results The most frequent tumours collected were: trichoblastoma (39.6%), basal cell carcinoma (20.7%) and syringocystadenoma papilliferum (15.6%). The most remarkable findings were: (i) the pattern composed of asymmetrical large blue-grey ovoid nests was more common in basal cell carcinomas than in trichoblastoma (58.3% vs. 4.3%; P <0.001) and the pattern composed of a symmetrical total large blue-grey ovoid nest (a blue-grey homogeneous area which occupies the whole lesion) was more common in trichoblastoma (82.6% vs. 16.6%; P <0.001); (ii) the most frequent pattern associated with syringocystadenoma papilliferum was a symmetric, erythematous lesion with exophytic papillary structures, ulceration and vessels (55.5%); (iii) the most common pattern associated with apocrine hidrocystomas was a total symmetric homogeneous area and arborizing telangiectasias (60%). Conclusions Benign adnexal tumours associated with naevus sebaceous are dermoscopic mimickers of basal cell carcinomas. A pigmented nodule arising in a naevus sebaceous with a total blue large ovoid nest on dermoscopy could be a trichoblastoma, basal cell carcinoma, hidrocystoma or hidradenoma. Dermoscopy can be a useful diagnostic tool which generates a more accurate preoperative diagnosis.
| Original language | English |
|---|---|
| Pages (from-to) | 2231-2237 |
| Number of pages | 7 |
| Journal | Journal of the European Academy of Dermatology and Venereology |
| Volume | 29 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Nov 1 2015 |
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ASJC Scopus subject areas
- Dermatology
- Infectious Diseases
Cite this
Dermoscopy of tumours arising in naevus sebaceous : A morphological study of 58 cases. / Zaballos, P.; Serrano, P.; Flores, G.; Bañuls, J.; Thomas, L.; Llambrich, A.; Castro, E.; Lallas, A.; Argenziano, G.; Zalaudek, I.; Del Pozo, L. J.; Landi, C.; Malvehy, J.
In: Journal of the European Academy of Dermatology and Venereology, Vol. 29, No. 11, 01.11.2015, p. 2231-2237.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dermoscopy of tumours arising in naevus sebaceous
T2 - A morphological study of 58 cases
AU - Zaballos, P.
AU - Serrano, P.
AU - Flores, G.
AU - Bañuls, J.
AU - Thomas, L.
AU - Llambrich, A.
AU - Castro, E.
AU - Lallas, A.
AU - Argenziano, G.
AU - Zalaudek, I.
AU - Del Pozo, L. J.
AU - Landi, C.
AU - Malvehy, J.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Background Naevus sebaceous is a congenital hamartoma commonly associated with the development of secondary neoplasms. There are sparse data relating to the dermoscopy of tumours arising in naevus sebaceous. Objectives To evaluate the dermoscopic features of a large series of neoplasms arising in naevus sebaceous. Methods Digital dermoscopic images of 58 histopathologically confirmed cases of secondary neoplasms arising in naevus sebaceous collected from 11 hospitals in Spain, France, Italy and Austria were evaluated for the presence of dermoscopic structures and patterns. Results The most frequent tumours collected were: trichoblastoma (39.6%), basal cell carcinoma (20.7%) and syringocystadenoma papilliferum (15.6%). The most remarkable findings were: (i) the pattern composed of asymmetrical large blue-grey ovoid nests was more common in basal cell carcinomas than in trichoblastoma (58.3% vs. 4.3%; P <0.001) and the pattern composed of a symmetrical total large blue-grey ovoid nest (a blue-grey homogeneous area which occupies the whole lesion) was more common in trichoblastoma (82.6% vs. 16.6%; P <0.001); (ii) the most frequent pattern associated with syringocystadenoma papilliferum was a symmetric, erythematous lesion with exophytic papillary structures, ulceration and vessels (55.5%); (iii) the most common pattern associated with apocrine hidrocystomas was a total symmetric homogeneous area and arborizing telangiectasias (60%). Conclusions Benign adnexal tumours associated with naevus sebaceous are dermoscopic mimickers of basal cell carcinomas. A pigmented nodule arising in a naevus sebaceous with a total blue large ovoid nest on dermoscopy could be a trichoblastoma, basal cell carcinoma, hidrocystoma or hidradenoma. Dermoscopy can be a useful diagnostic tool which generates a more accurate preoperative diagnosis.
AB - Background Naevus sebaceous is a congenital hamartoma commonly associated with the development of secondary neoplasms. There are sparse data relating to the dermoscopy of tumours arising in naevus sebaceous. Objectives To evaluate the dermoscopic features of a large series of neoplasms arising in naevus sebaceous. Methods Digital dermoscopic images of 58 histopathologically confirmed cases of secondary neoplasms arising in naevus sebaceous collected from 11 hospitals in Spain, France, Italy and Austria were evaluated for the presence of dermoscopic structures and patterns. Results The most frequent tumours collected were: trichoblastoma (39.6%), basal cell carcinoma (20.7%) and syringocystadenoma papilliferum (15.6%). The most remarkable findings were: (i) the pattern composed of asymmetrical large blue-grey ovoid nests was more common in basal cell carcinomas than in trichoblastoma (58.3% vs. 4.3%; P <0.001) and the pattern composed of a symmetrical total large blue-grey ovoid nest (a blue-grey homogeneous area which occupies the whole lesion) was more common in trichoblastoma (82.6% vs. 16.6%; P <0.001); (ii) the most frequent pattern associated with syringocystadenoma papilliferum was a symmetric, erythematous lesion with exophytic papillary structures, ulceration and vessels (55.5%); (iii) the most common pattern associated with apocrine hidrocystomas was a total symmetric homogeneous area and arborizing telangiectasias (60%). Conclusions Benign adnexal tumours associated with naevus sebaceous are dermoscopic mimickers of basal cell carcinomas. A pigmented nodule arising in a naevus sebaceous with a total blue large ovoid nest on dermoscopy could be a trichoblastoma, basal cell carcinoma, hidrocystoma or hidradenoma. Dermoscopy can be a useful diagnostic tool which generates a more accurate preoperative diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=84945434871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84945434871&partnerID=8YFLogxK
U2 - 10.1111/jdv.13226
DO - 10.1111/jdv.13226
M3 - Article
C2 - 26300536
AN - SCOPUS:84945434871
VL - 29
SP - 2231
EP - 2237
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
SN - 0926-9959
IS - 11
ER -