Abstract
We report a family of Algerian origin presenting an unusual, severe form of progressive myoclonus epilepsy characterized by myoclonus, generalized tonic-clonic seizures and moderate to severe cognitive impairment, with probable autosomal recessive inheritance. Disease onset was between 6 and 16 years of age. The diagnosis of Unverricht-Lundborg disease and all other known causes of progressive myoclonus epilepsies were excluded by specific laboratory tests and molecular analysis.
Original language | English |
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Pages (from-to) | 1016-1022 |
Number of pages | 7 |
Journal | Movement Disorders |
Volume | 24 |
Issue number | 7 |
DOIs | |
Publication status | Published - May 15 2009 |
Keywords
- Cognitive impairment
- Progressive myoclonus epilepsy
- Seizures
ASJC Scopus subject areas
- Clinical Neurology
- Neurology