Abstract
We report the identification of a novel HLA-DRB1*11 using sequence-based typing. This new allele, officially named DRB1*1150, was detected while performing HLA-DRB1 high-resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).
| Original language | English |
|---|---|
| Pages (from-to) | 298-299 |
| Number of pages | 2 |
| Journal | Tissue Antigens |
| Volume | 64 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 2004 |
Keywords
- DNA direct sequencing
- HLA-DRB1*11
ASJC Scopus subject areas
- Immunology
- Cell Biology
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Crespiatico, L., Frison, S., Andreini, E., Ferrioli, G., Rossi, U., & Poli, F. (2004). Description of a new HLA-DRB1 allele, DRB1*1150. Tissue Antigens, 64(3), 298-299. https://doi.org/10.1111/j.1399-0039.2004.00289.x