Abstract
We report the identification of a novel HLA-DRB1*11 using sequence-based typing. This new allele, officially named DRB1*1150, was detected while performing HLA-DRB1 high-resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).
| Original language | English |
|---|---|
| Pages (from-to) | 298-299 |
| Number of pages | 2 |
| Journal | Tissue Antigens |
| Volume | 64 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 2004 |
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Keywords
- DNA direct sequencing
- HLA-DRB1*11
ASJC Scopus subject areas
- Immunology
- Cell Biology
Cite this
Description of a new HLA-DRB1 allele, DRB1*1150. / Crespiatico, L.; Frison, S.; Andreini, E.; Ferrioli, G.; Rossi, U.; Poli, F.
In: Tissue Antigens, Vol. 64, No. 3, 09.2004, p. 298-299.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Description of a new HLA-DRB1 allele, DRB1*1150
AU - Crespiatico, L.
AU - Frison, S.
AU - Andreini, E.
AU - Ferrioli, G.
AU - Rossi, U.
AU - Poli, F.
PY - 2004/9
Y1 - 2004/9
N2 - We report the identification of a novel HLA-DRB1*11 using sequence-based typing. This new allele, officially named DRB1*1150, was detected while performing HLA-DRB1 high-resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).
AB - We report the identification of a novel HLA-DRB1*11 using sequence-based typing. This new allele, officially named DRB1*1150, was detected while performing HLA-DRB1 high-resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).
KW - DNA direct sequencing
KW - HLA-DRB111
UR - http://www.scopus.com/inward/record.url?scp=4344681445&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4344681445&partnerID=8YFLogxK
U2 - 10.1111/j.1399-0039.2004.00289.x
DO - 10.1111/j.1399-0039.2004.00289.x
M3 - Article
C2 - 15304012
AN - SCOPUS:4344681445
VL - 64
SP - 298
EP - 299
JO - Tissue Antigens
JF - Tissue Antigens
SN - 0001-2815
IS - 3
ER -