Description of a new HLA-DRB1 allele, DRB1*1150

L. Crespiatico, S. Frison, E. Andreini, G. Ferrioli, U. Rossi, F. Poli

Research output: Contribution to journalArticle

Abstract

We report the identification of a novel HLA-DRB1*11 using sequence-based typing. This new allele, officially named DRB1*1150, was detected while performing HLA-DRB1 high-resolution typing of a candidate for bone marrow transplantation. DRB1*1150 is identical to DRB1*1143 except at nucleotides 200 and 227, where a T is substituted by a C and a T by an A, respectively. These differences give rise to two amino acid substitutions at codons 38 (Val→Ala) and 47 (Phe→Tyr).

Original languageEnglish
Pages (from-to)298-299
Number of pages2
JournalTissue Antigens
Volume64
Issue number3
DOIs
Publication statusPublished - Sep 2004

Keywords

  • DNA direct sequencing
  • HLA-DRB1*11

ASJC Scopus subject areas

  • Immunology
  • Cell Biology

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    Crespiatico, L., Frison, S., Andreini, E., Ferrioli, G., Rossi, U., & Poli, F. (2004). Description of a new HLA-DRB1 allele, DRB1*1150. Tissue Antigens, 64(3), 298-299. https://doi.org/10.1111/j.1399-0039.2004.00289.x