Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporine

Claudio Ponticelli, A. Tarantino, A. Aroldi, V. Sparacino, S. Stefoni, F. Citterio, L. Duca, M. P. Scolari, S. Calabrese, P. Altieri, G. Civati, B. Cesana

Research output: Contribution to journalArticle

Abstract

We present the study design of a prospective, multicenter, randomized trial aimed at comparing the effects of two different combinations of sirolimus. Renal transplant recipients will be allocated to receive either sirolimus and mycophenolate mofetil (group A) or sirolimus and cyclosporine (group B). The primary endpoint will be the graft function at 3, 6, 12, 24, 36, 48, and 60 months. A number of secondary endpoints will also be considered. To obtain a significant difference in the primary endpoint 180 patients will be enrolled.

Original languageEnglish
JournalTransplantation Proceedings
Volume35
Issue number3 SUPPL.
DOIs
Publication statusPublished - May 2003

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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