Design Techniques to Optimize the Scaffold Performance: Freeze-dried Bone Custom-made Allografts for Maxillary Alveolar Horizontal Ridge Augmentation

Felice Roberto Grassi, Roberta Grassi, Leonardo Vivarelli, Dante Dallari, Marco Govoni, Gianna Maria Nardi, Zamira Kalemaj, Andrea Ballini

Research output: Contribution to journalArticle

Abstract

The purpose of the current investigation was to evaluate the clinical success of horizontal ridge augmentation in severely atrophic maxilla (Cawood and Howell class IV) using freeze-dried custom made bone harvested from the tibial hemiplateau of cadaver donors, and to analyze the marginal bone level gain prior to dental implant placement at nine months subsequent to bone grafting and before prosthetic rehabilitation. A 52-year-old woman received custom made bone grafts. The patient underwent CT scans two weeks prior and nine months after surgery for graft volume and density analysis. The clinical and radiographic bone observations showed a very low rate of resorption after bone graft and implant placement. The custom-made allograft material was a highly effective modality for restoring the alveolar horizontal ridge, resulting in a reduction of the need to obtain autogenous bone from a secondary site with predictable procedure. Further studies are needed to investigate its behavior at longer time periods.

Original languageEnglish
JournalMaterials
Volume13
Issue number6
DOIs
Publication statusPublished - Mar 19 2020

Keywords

  • allograft
  • block bone grafts
  • custom made bone
  • design techniques for scaffold
  • geometry optimization of scaffolds
  • precision and translational medicine

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