Detailed spatiotemporal brain mapping of chromatic vision combining high-resolution VEP with fMRI and retinotopy

Sabrina Pitzalis, Francesca Strappini, Alessandro Bultrini, Francesco Di Russo

Research output: Contribution to journalArticle

Abstract

Neuroimaging studies have identified so far, several color-sensitive visual areas in the human brain, and the temporal dynamics of these activities have been separately investigated using the visual-evoked potentials (VEPs). In the present study, we combined electrophysiological and neuroimaging methods to determine a detailed spatiotemporal profile of chromatic VEP and to localize its neural generators. The accuracy of the present co-registration study was obtained by combining standard fMRI data with retinotopic and motion mapping data at the individual level. We found a sequence of occipito activities more complex than that typically reported for chromatic VEPs, including feed-forward and reentrant feedback. Results showed that chromatic human perception arises by the combined activity of at the least five parieto-occipital areas including V1, LOC, V8/VO, and the motion-sensitive dorsal region MT+. However, the contribution of V1 and V8/VO seems dominant because the re-entrant activity in these areas was present more than once (twice in V8/VO and thrice in V1). This feedforward and feedback chromatic processing appears delayed compared with the luminance processing. Associating VEPs and neuroimaging measures, we showed for the first time a complex spatiotemporal pattern of activity, confirming that chromatic stimuli produce intricate interactions of many different brain dorsal and ventral areas.

Original languageEnglish
Pages (from-to)2868-2886
Number of pages19
JournalHuman Brain Mapping
Volume39
Issue number7
DOIs
Publication statusPublished - Jul 1 2018

Fingerprint

Brain Mapping
Color Vision
Visual Evoked Potentials
Color
Magnetic Resonance Imaging
Neuroimaging
Color Perception
Brain

Keywords

  • color
  • ERP
  • human
  • retinotopic maps
  • V8/VO

ASJC Scopus subject areas

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Cite this

Detailed spatiotemporal brain mapping of chromatic vision combining high-resolution VEP with fMRI and retinotopy. / Pitzalis, Sabrina; Strappini, Francesca; Bultrini, Alessandro; Di Russo, Francesco.

In: Human Brain Mapping, Vol. 39, No. 7, 01.07.2018, p. 2868-2886.

Research output: Contribution to journalArticle

Pitzalis, Sabrina ; Strappini, Francesca ; Bultrini, Alessandro ; Di Russo, Francesco. / Detailed spatiotemporal brain mapping of chromatic vision combining high-resolution VEP with fMRI and retinotopy. In: Human Brain Mapping. 2018 ; Vol. 39, No. 7. pp. 2868-2886.
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