Abstract
High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS) was used to detect illicit drugs and metabolites in wastewater. Cocaine, amphetamines, morphine and derivatives, the main metabolite of tetahydrocannabinol (THC-COOH) methadone and some of their metabolites in wastewater was developed by using solid phase extraction (SPE) and HPLC-MS. Two main factors, matrix effect and sensitivity were carefully considered to optimize the analytical conditions in wastewater. Samples were collected from the influent and effluent wastewater of a treatment plant. Drugs were analyzed using an XTerra MS C18, 100×2.1 mm, 3.5«mu»m columns at a flow rate of 200«mu»L min-1. The mass spectrometer system was an API 3000 triple quadrupole mass spectrometer, equipped with a turbo ion spray source. The presence of these substances in WWTPs was verified, and each compound was quantified in both the influents and effluents.
| Original language | English |
|---|---|
| Pages (from-to) | 7-9 |
| Number of pages | 3 |
| Journal | Spectroscopy Europe |
| Volume | 19 |
| Issue number | 4 |
| Publication status | Published - Aug 2007 |
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ASJC Scopus subject areas
- Instrumentation
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Detecting illicit drugs and metabolites in wastewater using high performance liquid chromatography-tandem mass spectrometry. / Castiglioni, Sara; Zuccato, Ettore; Chiabrando, Chiara; Fanelli, Roberto; Bagnati, Renzo.
In: Spectroscopy Europe, Vol. 19, No. 4, 08.2007, p. 7-9.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Detecting illicit drugs and metabolites in wastewater using high performance liquid chromatography-tandem mass spectrometry
AU - Castiglioni, Sara
AU - Zuccato, Ettore
AU - Chiabrando, Chiara
AU - Fanelli, Roberto
AU - Bagnati, Renzo
PY - 2007/8
Y1 - 2007/8
N2 - High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS) was used to detect illicit drugs and metabolites in wastewater. Cocaine, amphetamines, morphine and derivatives, the main metabolite of tetahydrocannabinol (THC-COOH) methadone and some of their metabolites in wastewater was developed by using solid phase extraction (SPE) and HPLC-MS. Two main factors, matrix effect and sensitivity were carefully considered to optimize the analytical conditions in wastewater. Samples were collected from the influent and effluent wastewater of a treatment plant. Drugs were analyzed using an XTerra MS C18, 100×2.1 mm, 3.5«mu»m columns at a flow rate of 200«mu»L min-1. The mass spectrometer system was an API 3000 triple quadrupole mass spectrometer, equipped with a turbo ion spray source. The presence of these substances in WWTPs was verified, and each compound was quantified in both the influents and effluents.
AB - High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS) was used to detect illicit drugs and metabolites in wastewater. Cocaine, amphetamines, morphine and derivatives, the main metabolite of tetahydrocannabinol (THC-COOH) methadone and some of their metabolites in wastewater was developed by using solid phase extraction (SPE) and HPLC-MS. Two main factors, matrix effect and sensitivity were carefully considered to optimize the analytical conditions in wastewater. Samples were collected from the influent and effluent wastewater of a treatment plant. Drugs were analyzed using an XTerra MS C18, 100×2.1 mm, 3.5«mu»m columns at a flow rate of 200«mu»L min-1. The mass spectrometer system was an API 3000 triple quadrupole mass spectrometer, equipped with a turbo ion spray source. The presence of these substances in WWTPs was verified, and each compound was quantified in both the influents and effluents.
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M3 - Article
AN - SCOPUS:49549111829
VL - 19
SP - 7
EP - 9
JO - Spectroscopy Europe
JF - Spectroscopy Europe
SN - 0966-0941
IS - 4
ER -