Detection and Morphology of Thymic Remnants after Video-Assisted Thoracoscopic Extended Thymectomy (VATET) in Patients with Myasthenia Gravis R

R. Scelsi, M. T. Ferrò, L. Scelsi, L. Novellino, R. Mantegazza, F. Cornelio, M. Porta, C. Longoni, G. Pezzuoli

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Thymectomy is often an extremely useful therapeutic procedure in myasthenia gravis (MG) and is usually indicated for adult patients with generalized disease. Because remnants of thymus may remain in extrathymic fat, an extended thymectomy is recommended. A new surgical approach without sternotomy: video-assisted thoracoscopic extended thymectomy (VATET) was performed in 30 MG patients. The weight of removed thymus ranged from 10.8 to 113 grams. The weight of fatty tissue removed from pretracheal, anterior mediastinal and costophrenic areas ranged from 6.3 to 74.8 grams. Histological examination revealed thymic remnants in 14.8% of pretracheal fat samples and in 33.3% of samples from anterior mediastinal plus costophrenic areas. These findings indicate that VATET is a radical procedure and may be the first choice surgery for young female MG patients, since aesthetic sequelae are reduced compared to procedures involving sternotomy.

Original languageEnglish
Pages (from-to)14-17
Number of pages4
JournalInternational Surgery
Volume81
Issue number1
Publication statusPublished - Jan 1996

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Thymectomy
Myasthenia Gravis
Sternotomy
Thymus Gland
Fats
Weights and Measures
Esthetics
Adipose Tissue
Therapeutics

Keywords

  • Histology
  • Myasthenia gravis
  • Thymectomy, video-assisted thoracoscopic extended
  • Thymic remnants

ASJC Scopus subject areas

  • Medicine(all)
  • Surgery

Cite this

Detection and Morphology of Thymic Remnants after Video-Assisted Thoracoscopic Extended Thymectomy (VATET) in Patients with Myasthenia Gravis R. / Scelsi, R.; Ferrò, M. T.; Scelsi, L.; Novellino, L.; Mantegazza, R.; Cornelio, F.; Porta, M.; Longoni, C.; Pezzuoli, G.

In: International Surgery, Vol. 81, No. 1, 01.1996, p. 14-17.

Research output: Contribution to journalArticle

Scelsi, R, Ferrò, MT, Scelsi, L, Novellino, L, Mantegazza, R, Cornelio, F, Porta, M, Longoni, C & Pezzuoli, G 1996, 'Detection and Morphology of Thymic Remnants after Video-Assisted Thoracoscopic Extended Thymectomy (VATET) in Patients with Myasthenia Gravis R', International Surgery, vol. 81, no. 1, pp. 14-17.
Scelsi, R. ; Ferrò, M. T. ; Scelsi, L. ; Novellino, L. ; Mantegazza, R. ; Cornelio, F. ; Porta, M. ; Longoni, C. ; Pezzuoli, G. / Detection and Morphology of Thymic Remnants after Video-Assisted Thoracoscopic Extended Thymectomy (VATET) in Patients with Myasthenia Gravis R. In: International Surgery. 1996 ; Vol. 81, No. 1. pp. 14-17.
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