Detection of a case of pseudolymphocytosis due to cryoglobulins

G. Banfi, V. Grazioli, A. Dolci, M. Murone, P. A. Bonini

Research output: Contribution to journalArticle

Abstract

A new type of interference of cryoglobulins on hemocytometric tests is described. The precipitation of temperature-dependent proteins produced a pseudolymphocytosis on a three-part differential leukocyte count of Coulter S-Plus VI, whereas unaffected results, identical to the microscopical count, were obtained using the cytometer Coulter VCS. The laboratory detection of cryoglobulin interference on hematological data is very important in patients with underlying diseases, where the accuracy of absolute and differential leukocyte counts is critical for follow-up. Histograms from the Coulter S-Plus VI can help detect these cases.

Original languageEnglish
Pages (from-to)319-323
Number of pages5
JournalJournal of Clinical Laboratory Analysis
Volume4
Issue number5
Publication statusPublished - 1990

Fingerprint

Cryoglobulins
Leukocyte Count
Temperature
Proteins

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Banfi, G., Grazioli, V., Dolci, A., Murone, M., & Bonini, P. A. (1990). Detection of a case of pseudolymphocytosis due to cryoglobulins. Journal of Clinical Laboratory Analysis, 4(5), 319-323.

Detection of a case of pseudolymphocytosis due to cryoglobulins. / Banfi, G.; Grazioli, V.; Dolci, A.; Murone, M.; Bonini, P. A.

In: Journal of Clinical Laboratory Analysis, Vol. 4, No. 5, 1990, p. 319-323.

Research output: Contribution to journalArticle

Banfi, G, Grazioli, V, Dolci, A, Murone, M & Bonini, PA 1990, 'Detection of a case of pseudolymphocytosis due to cryoglobulins', Journal of Clinical Laboratory Analysis, vol. 4, no. 5, pp. 319-323.
Banfi, G. ; Grazioli, V. ; Dolci, A. ; Murone, M. ; Bonini, P. A. / Detection of a case of pseudolymphocytosis due to cryoglobulins. In: Journal of Clinical Laboratory Analysis. 1990 ; Vol. 4, No. 5. pp. 319-323.
@article{4d85b084a0f04fbdb42c40fca26c1900,
title = "Detection of a case of pseudolymphocytosis due to cryoglobulins",
abstract = "A new type of interference of cryoglobulins on hemocytometric tests is described. The precipitation of temperature-dependent proteins produced a pseudolymphocytosis on a three-part differential leukocyte count of Coulter S-Plus VI, whereas unaffected results, identical to the microscopical count, were obtained using the cytometer Coulter VCS. The laboratory detection of cryoglobulin interference on hematological data is very important in patients with underlying diseases, where the accuracy of absolute and differential leukocyte counts is critical for follow-up. Histograms from the Coulter S-Plus VI can help detect these cases.",
author = "G. Banfi and V. Grazioli and A. Dolci and M. Murone and Bonini, {P. A.}",
year = "1990",
language = "English",
volume = "4",
pages = "319--323",
journal = "Journal of Clinical Laboratory Analysis",
issn = "0887-8013",
publisher = "Wiley-Liss Inc.",
number = "5",

}

TY - JOUR

T1 - Detection of a case of pseudolymphocytosis due to cryoglobulins

AU - Banfi, G.

AU - Grazioli, V.

AU - Dolci, A.

AU - Murone, M.

AU - Bonini, P. A.

PY - 1990

Y1 - 1990

N2 - A new type of interference of cryoglobulins on hemocytometric tests is described. The precipitation of temperature-dependent proteins produced a pseudolymphocytosis on a three-part differential leukocyte count of Coulter S-Plus VI, whereas unaffected results, identical to the microscopical count, were obtained using the cytometer Coulter VCS. The laboratory detection of cryoglobulin interference on hematological data is very important in patients with underlying diseases, where the accuracy of absolute and differential leukocyte counts is critical for follow-up. Histograms from the Coulter S-Plus VI can help detect these cases.

AB - A new type of interference of cryoglobulins on hemocytometric tests is described. The precipitation of temperature-dependent proteins produced a pseudolymphocytosis on a three-part differential leukocyte count of Coulter S-Plus VI, whereas unaffected results, identical to the microscopical count, were obtained using the cytometer Coulter VCS. The laboratory detection of cryoglobulin interference on hematological data is very important in patients with underlying diseases, where the accuracy of absolute and differential leukocyte counts is critical for follow-up. Histograms from the Coulter S-Plus VI can help detect these cases.

UR - http://www.scopus.com/inward/record.url?scp=0025086682&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025086682&partnerID=8YFLogxK

M3 - Article

C2 - 2231178

AN - SCOPUS:0025086682

VL - 4

SP - 319

EP - 323

JO - Journal of Clinical Laboratory Analysis

JF - Journal of Clinical Laboratory Analysis

SN - 0887-8013

IS - 5

ER -