Abstract
Chromosome analysis was performed on successive cultures of fibroblasts from the parents of two trisomic 21 patients. Starting from the 7th passage in the father cultures an aneuploid clone showing an extra E like chromosome was found, which eventually overgrew the cell population. The significance of this cytogenetic finding is discussed in relation to the recurrence of the trisomy in the family.
Original language | English |
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Pages (from-to) | 169-171 |
Number of pages | 3 |
Journal | Annales de Genetique |
Volume | 19 |
Issue number | 3 |
Publication status | Published - 1976 |
ASJC Scopus subject areas
- Genetics