Detection of cardiac arrhythmias and ischaemic events in combination chemotherapy with Cisplatin, Etoposide and Bleomycin for testicular cancer

R. Comazzi, D. Misrachi, M. Galimberti, L. Piva, G. Pizzoccaro, F. Villani

Research output: Contribution to journalArticle

Abstract

Ten patients treated with combination chemotherapy regimen containing Cisplatin, Bleomycin and Etoposide (PEB) were submitted to Holter monitoring during the first cycle of treatment. No modifications of heart rate, ST-T segment were observed and only a slight increase of incidence of sopraventricular ectopic beats was recorded. One patient developed a transient second degree atrio-ventricular block in the first day during episodes of vomiting. These data suggest that combination chemotherapy with PEB, at least during the first cycle of treatment, has no significant arrhythmogenic effect.

Original languageEnglish
Pages (from-to)663-665
Number of pages3
JournalAnticancer Research
Volume9
Issue number3
Publication statusPublished - 1989

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ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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