We describe the use of a polymerase chain reaction-based method followed by a DNA enzyme immunoassay for the simultaneous detection of the eight most common β-thalassemia mutations in the Mediterranean population. The method is specific, sensitive, and easily applicable in routine clinical laboratories for the molecular diagnosis of β-thalassemia patients and at risk couples.
|Number of pages||4|
|Journal||International Journal of Clinical & Laboratory Research|
|Publication status||Published - Jul 1996|
- DNA enzyme immunoassay
- Polymerase chain reaction
ASJC Scopus subject areas
- Clinical Biochemistry