Detection of HIV-1 genome in leukocytes of human colostrum from anti-HIV-1 seropositive mothers

N. Vonesch, E. Sturchio, A. C. Humani, P. C. Fei, D. Cosenza, F. Caprilli, M. Pezzella

Research output: Contribution to journalArticlepeer-review

Abstract

In order to obtain more information about the presence of HIV-1 in mononuclear cells of colostrum, research was carried out on both the HIV-1 genome in the cellular fraction of colostrum and the viral antibody in cell- free colostrum of eight anti-HIV-1 seropositive asymptomatic mothers. In five cases cell fractions of the colostrum harbored HIV-1 genome by DNA-DNA and DNA-RNA in situ hybridization, whereas viral antibody were detected in all cell-free colostrum specimens. The data confirms the colostrum as a possible route of HIV-1 infection.

Original languageEnglish
Pages (from-to)1283-1287
Number of pages5
JournalAIDS Research and Human Retroviruses
Volume8
Issue number7
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Immunology
  • Virology

Fingerprint

Dive into the research topics of 'Detection of HIV-1 genome in leukocytes of human colostrum from anti-HIV-1 seropositive mothers'. Together they form a unique fingerprint.

Cite this