A simple immunohistological test has been developed to detect and to quanti-tate the presence of immune complexes (IC) on the surface of human polymorphonuclear neutrophils (PMN). The interaction between IC and PMN has been evaluated in several human IC diseases. High amounts of immunoglobulins (Ig) and C3were detected on the PMN surface from these patients. The deposits of Ig and C3were inversely related to the percentage of membrane-free receptors for Fc and C3.
ASJC Scopus subject areas
- Immunology and Allergy