Detection of leptomeningeal involvement by 18F-FDG-PET/CT in a patient with non-Hodgkin lymphoma

Rosa Fonti, Barbara Salvatore, Amalia De Renzo, Emanuele Nicolai, Silvana Del Vecchio

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Leptomeningeal infiltration of the brain or spinal cord by neoplastic cells may occur as complication of solid or hematopoietic tumors such as non-Hodgkin lymphoma. Previously rare, this event is becoming increasingly common as newer therapies can prolong survival but may not achieve therapeutic concentration in the central nervous system. Although prognosis is poor, early diagnosis and aggressive treatment may lead to prolonged survival and/or improvement of quality of life. We report a case of a 69-year-old man with leptomeningeal infiltration by non-Hodgkin lymphoma revealed by 18F-FDG-PET/CT and confirmed by subsequent spinal MRI and cerebrospinal fluid cytology.

Original languageEnglish
Pages (from-to)169-172
Number of pages4
JournalClinical Nuclear Medicine
Volume41
Issue number2
DOIs
Publication statusPublished - Nov 6 2015

Fingerprint

Fluorodeoxyglucose F18
Non-Hodgkin's Lymphoma
Survival
Cell Biology
Cerebrospinal Fluid
Early Diagnosis
Spinal Cord
Therapeutics
Central Nervous System
Quality of Life
Brain
Neoplasms

Keywords

  • F-FDG-PET/CT
  • Leptomeningeal involvement
  • MRI
  • Non-Hodgkin lymphoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Detection of leptomeningeal involvement by 18F-FDG-PET/CT in a patient with non-Hodgkin lymphoma. / Fonti, Rosa; Salvatore, Barbara; De Renzo, Amalia; Nicolai, Emanuele; Del Vecchio, Silvana.

In: Clinical Nuclear Medicine, Vol. 41, No. 2, 06.11.2015, p. 169-172.

Research output: Contribution to journalArticle

Fonti, Rosa ; Salvatore, Barbara ; De Renzo, Amalia ; Nicolai, Emanuele ; Del Vecchio, Silvana. / Detection of leptomeningeal involvement by 18F-FDG-PET/CT in a patient with non-Hodgkin lymphoma. In: Clinical Nuclear Medicine. 2015 ; Vol. 41, No. 2. pp. 169-172.
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