Detection of multiple sclerosis lesions using EPI-FLAIR images

Marco Rovaris, Giuseppe Iannucci, Clodoaldo Pereira, Giancarlo Comi, Massimo Filippi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Fast fluid-attenuated inversion recovery (fast-FLAIR) sequences are very sensitive for detecting lesions of patients with multiple sclerosis (MS). Echo planar imaging allows to obtain FLAIR images (EPI-FLAIR) with significantly shorter scanning times. EPI-FLAIR images obtained with 10 measurements are as sensitive as fast-FLAIR for the detection of large MS lesions. Aim of this study was to compare the numbers of MS lesions seen on EPI-FLAIR images with fewer measurements (and, as a consequence, very short scanning times) with those seen on EPI-FLAIR images with 10 measurements. EPI-FLAIR scans with 2 (EPI-2), 4 (EPI-4), 6 (EPI-6), 8 (EPI-8) and 10 (EPI-10) measurements were obtained from 29 MS patients. Lesions seen using each of the five approaches were counted by agreement by two observers. EPI-10 images were used as the 'gold standard' for pairwise comparisons. EPI-FLAIR scans with fewer measurements (EPI-2, -4, -6, -8) were all significantly less sensitive than EPI-10 for the detection of small, intermediate and large MS lesions. All the EPI-FLAIR scans, however, fulfilled MR diagnostic criteria for definite MS. When rapid MR scanning of uncooperative MS patients is needed, EPI-FLAIR images coveting the entire brain in less than one minute may be considered. (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)907-910
Number of pages4
JournalMagnetic Resonance Imaging
Volume18
Issue number7
DOIs
Publication statusPublished - 2000

Fingerprint

lesions
Multiple Sclerosis
Scanning
scanning
Recovery
recovery
Fluids
inversions
Sequence Inversion
Echo-Planar Imaging
fluids
Brain
brain
echoes
Imaging techniques

Keywords

  • EPI-FLAIR
  • FLAIR
  • Magnetic resonance
  • Multiple sclerosis

ASJC Scopus subject areas

  • Biophysics
  • Clinical Biochemistry
  • Structural Biology
  • Radiology Nuclear Medicine and imaging
  • Condensed Matter Physics

Cite this

Detection of multiple sclerosis lesions using EPI-FLAIR images. / Rovaris, Marco; Iannucci, Giuseppe; Pereira, Clodoaldo; Comi, Giancarlo; Filippi, Massimo.

In: Magnetic Resonance Imaging, Vol. 18, No. 7, 2000, p. 907-910.

Research output: Contribution to journalArticle

@article{0a6f78901eed43ed94a14a494e6182a0,
title = "Detection of multiple sclerosis lesions using EPI-FLAIR images",
abstract = "Fast fluid-attenuated inversion recovery (fast-FLAIR) sequences are very sensitive for detecting lesions of patients with multiple sclerosis (MS). Echo planar imaging allows to obtain FLAIR images (EPI-FLAIR) with significantly shorter scanning times. EPI-FLAIR images obtained with 10 measurements are as sensitive as fast-FLAIR for the detection of large MS lesions. Aim of this study was to compare the numbers of MS lesions seen on EPI-FLAIR images with fewer measurements (and, as a consequence, very short scanning times) with those seen on EPI-FLAIR images with 10 measurements. EPI-FLAIR scans with 2 (EPI-2), 4 (EPI-4), 6 (EPI-6), 8 (EPI-8) and 10 (EPI-10) measurements were obtained from 29 MS patients. Lesions seen using each of the five approaches were counted by agreement by two observers. EPI-10 images were used as the 'gold standard' for pairwise comparisons. EPI-FLAIR scans with fewer measurements (EPI-2, -4, -6, -8) were all significantly less sensitive than EPI-10 for the detection of small, intermediate and large MS lesions. All the EPI-FLAIR scans, however, fulfilled MR diagnostic criteria for definite MS. When rapid MR scanning of uncooperative MS patients is needed, EPI-FLAIR images coveting the entire brain in less than one minute may be considered. (C) 2000 Elsevier Science Inc.",
keywords = "EPI-FLAIR, FLAIR, Magnetic resonance, Multiple sclerosis",
author = "Marco Rovaris and Giuseppe Iannucci and Clodoaldo Pereira and Giancarlo Comi and Massimo Filippi",
year = "2000",
doi = "10.1016/S0730-725X(00)00166-1",
language = "English",
volume = "18",
pages = "907--910",
journal = "Magnetic Resonance Imaging",
issn = "0730-725X",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Detection of multiple sclerosis lesions using EPI-FLAIR images

AU - Rovaris, Marco

AU - Iannucci, Giuseppe

AU - Pereira, Clodoaldo

AU - Comi, Giancarlo

AU - Filippi, Massimo

PY - 2000

Y1 - 2000

N2 - Fast fluid-attenuated inversion recovery (fast-FLAIR) sequences are very sensitive for detecting lesions of patients with multiple sclerosis (MS). Echo planar imaging allows to obtain FLAIR images (EPI-FLAIR) with significantly shorter scanning times. EPI-FLAIR images obtained with 10 measurements are as sensitive as fast-FLAIR for the detection of large MS lesions. Aim of this study was to compare the numbers of MS lesions seen on EPI-FLAIR images with fewer measurements (and, as a consequence, very short scanning times) with those seen on EPI-FLAIR images with 10 measurements. EPI-FLAIR scans with 2 (EPI-2), 4 (EPI-4), 6 (EPI-6), 8 (EPI-8) and 10 (EPI-10) measurements were obtained from 29 MS patients. Lesions seen using each of the five approaches were counted by agreement by two observers. EPI-10 images were used as the 'gold standard' for pairwise comparisons. EPI-FLAIR scans with fewer measurements (EPI-2, -4, -6, -8) were all significantly less sensitive than EPI-10 for the detection of small, intermediate and large MS lesions. All the EPI-FLAIR scans, however, fulfilled MR diagnostic criteria for definite MS. When rapid MR scanning of uncooperative MS patients is needed, EPI-FLAIR images coveting the entire brain in less than one minute may be considered. (C) 2000 Elsevier Science Inc.

AB - Fast fluid-attenuated inversion recovery (fast-FLAIR) sequences are very sensitive for detecting lesions of patients with multiple sclerosis (MS). Echo planar imaging allows to obtain FLAIR images (EPI-FLAIR) with significantly shorter scanning times. EPI-FLAIR images obtained with 10 measurements are as sensitive as fast-FLAIR for the detection of large MS lesions. Aim of this study was to compare the numbers of MS lesions seen on EPI-FLAIR images with fewer measurements (and, as a consequence, very short scanning times) with those seen on EPI-FLAIR images with 10 measurements. EPI-FLAIR scans with 2 (EPI-2), 4 (EPI-4), 6 (EPI-6), 8 (EPI-8) and 10 (EPI-10) measurements were obtained from 29 MS patients. Lesions seen using each of the five approaches were counted by agreement by two observers. EPI-10 images were used as the 'gold standard' for pairwise comparisons. EPI-FLAIR scans with fewer measurements (EPI-2, -4, -6, -8) were all significantly less sensitive than EPI-10 for the detection of small, intermediate and large MS lesions. All the EPI-FLAIR scans, however, fulfilled MR diagnostic criteria for definite MS. When rapid MR scanning of uncooperative MS patients is needed, EPI-FLAIR images coveting the entire brain in less than one minute may be considered. (C) 2000 Elsevier Science Inc.

KW - EPI-FLAIR

KW - FLAIR

KW - Magnetic resonance

KW - Multiple sclerosis

UR - http://www.scopus.com/inward/record.url?scp=0033776722&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033776722&partnerID=8YFLogxK

U2 - 10.1016/S0730-725X(00)00166-1

DO - 10.1016/S0730-725X(00)00166-1

M3 - Article

VL - 18

SP - 907

EP - 910

JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

SN - 0730-725X

IS - 7

ER -