Determinant role of short-term heart rate variability in the prediction of mortality in patients with chronic heart failure

G. D. Pinna, R. Maestri, S. Capomolla, O. Febo, A. Mortara, P. G. Riccardi, M. T. La Rovere

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

The identification of prognostic indexes of sudden death represents a major challenge in the management of patients with chronic heart failure (CHF). In this study we present the results of a prospective study on 382 patients aimed at assessing the prognostic value of long- and short-term heart rate variability (HRV) parameters. Survival analysis (Cox model) was performed considering as covariates a set of clinical and functional parameters, including echocardiographic measurements, hemodynamic and exercise testing parameters, blood examinations, 24-hour arrhythmia data and NYHA class, well known to be predictors of total cardiac death. Two final multivariate prognostic models were identified, both containing the short-term low frequency (0.04-0.045 Hz) power during controlled breathing as independent and strongest predictor of sudden death. Model covariates in the two models were respectively the number of premature ventricular contractions per hour and left ventricular ejection fraction.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages735-738
Number of pages4
Publication statusPublished - 2000

Fingerprint

Sudden Death
Heart Failure
Heart Rate
Ventricular Premature Complexes
Mortality
Survival Analysis
Proportional Hazards Models
Stroke Volume
Cardiac Arrhythmias
Respiration
Hemodynamics
Prospective Studies
Exercise
Blood
Testing

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

Cite this

Pinna, G. D., Maestri, R., Capomolla, S., Febo, O., Mortara, A., Riccardi, P. G., & La Rovere, M. T. (2000). Determinant role of short-term heart rate variability in the prediction of mortality in patients with chronic heart failure. In Computers in Cardiology (pp. 735-738). IEEE.

Determinant role of short-term heart rate variability in the prediction of mortality in patients with chronic heart failure. / Pinna, G. D.; Maestri, R.; Capomolla, S.; Febo, O.; Mortara, A.; Riccardi, P. G.; La Rovere, M. T.

Computers in Cardiology. IEEE, 2000. p. 735-738.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pinna GD, Maestri R, Capomolla S, Febo O, Mortara A, Riccardi PG et al. Determinant role of short-term heart rate variability in the prediction of mortality in patients with chronic heart failure. In Computers in Cardiology. IEEE. 2000. p. 735-738
Pinna, G. D. ; Maestri, R. ; Capomolla, S. ; Febo, O. ; Mortara, A. ; Riccardi, P. G. ; La Rovere, M. T. / Determinant role of short-term heart rate variability in the prediction of mortality in patients with chronic heart failure. Computers in Cardiology. IEEE, 2000. pp. 735-738
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