Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: Results from a prospective multicentric study in Italy

F. Parazzini, V. Mais, S. Cipriani, M. Busacca, P. Venturini

Research output: Contribution to journalArticle

Abstract

Objective: We conducted a cross-sectional study on the frequency and risk factors for adenomyosis in women who underwent hysterectomy for benign gynecological conditions. Study design: All women who consecutively underwent hysterectomy during the study period for benign gynecological conditions at 18 gynecological departments were eligible for the study. A total of 820 women entered the study. Pathological data were collected prospectically. Results: Adenomyosis was identified in 231 women (28.2%, 95% confidence interval, CI, 24.6-32.5). The frequency of adenomyosis was similar in women with indication for surgery fibroids/menorrhagia (143 cases, 28.5%) or genital prolapse (69 cases, 28.2%). The rate ratio (RR) of adenomyosis was 1.9 (95% CI 1.2-2.8) in women reporting one or more induced abortions, in comparison with those reporting no induced abortion. Women with adenomyosis reported more frequently dysmenorrhoea and chronic pelvic pain, but not dyspareunia. Conclusions: This study shows that adenomyosis is common in women who undergo hysterectomy and that it is more frequent among women reporting induced abortions dysmenorrhoea and chronic pelvic pain.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
Volume143
Issue number2
DOIs
Publication statusPublished - Apr 2009

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Adenomyosis
Hysterectomy
Italy
Prospective Studies
Induced Abortion
Dysmenorrhea
Pelvic Pain
Chronic Pain
Dyspareunia
Menorrhagia
Prolapse
Leiomyoma
Cross-Sectional Studies
Confidence Intervals

Keywords

  • Adenomyosis
  • Epidemiology
  • Risk factor

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

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title = "Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: Results from a prospective multicentric study in Italy",
abstract = "Objective: We conducted a cross-sectional study on the frequency and risk factors for adenomyosis in women who underwent hysterectomy for benign gynecological conditions. Study design: All women who consecutively underwent hysterectomy during the study period for benign gynecological conditions at 18 gynecological departments were eligible for the study. A total of 820 women entered the study. Pathological data were collected prospectically. Results: Adenomyosis was identified in 231 women (28.2{\%}, 95{\%} confidence interval, CI, 24.6-32.5). The frequency of adenomyosis was similar in women with indication for surgery fibroids/menorrhagia (143 cases, 28.5{\%}) or genital prolapse (69 cases, 28.2{\%}). The rate ratio (RR) of adenomyosis was 1.9 (95{\%} CI 1.2-2.8) in women reporting one or more induced abortions, in comparison with those reporting no induced abortion. Women with adenomyosis reported more frequently dysmenorrhoea and chronic pelvic pain, but not dyspareunia. Conclusions: This study shows that adenomyosis is common in women who undergo hysterectomy and that it is more frequent among women reporting induced abortions dysmenorrhoea and chronic pelvic pain.",
keywords = "Adenomyosis, Epidemiology, Risk factor",
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AU - Mais, V.

AU - Cipriani, S.

AU - Busacca, M.

AU - Venturini, P.

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