Determinants of age at menopause in Italy: Results from a large cross-sectional study

Michele Meschia, Francesco Pansini, Alberto Bacchi Modena, Domenico De Aloysio, Marco Gambacciani, Fabio Parazzini, Carlo Campagnoli, Giuseppe Maiocchi, Elena Peruzzi

Research output: Contribution to journalArticlepeer-review


Objective: To identify the determinants of age at menopause in an Italian population, using data from the Italian Climacteric Research Group Study (ICARUS). Methods: ICARUS is a prospective study of the effect of menopause on women's health that has been running in menopause clinics throughout Italy since 1995. A total of 4300 women with spontaneous menopause, aged 55 years or more and observed for the first time at the participating centres are included in the present analysis. Results: The mean age at menopause in the total population was 50.9 years. After taking into account potential covariates, the women reported smoking, had a slightly lower mean age at menopause than non smokers 50.4 versus 50.9 years; P=0.01. The mean age at menopause in nulliparae was 50.0 years, and, respectively 50.4, 50.6, 50.9, 51.2 and 50.9 years in those reporting 1, 2, 3, 4 and 5 or more births (P

Original languageEnglish
Pages (from-to)119-125
Number of pages7
Issue number2
Publication statusPublished - Feb 15 2000


  • Epidemiology
  • Menopause
  • Risk factors

ASJC Scopus subject areas

  • Ageing
  • Obstetrics and Gynaecology


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