Determinants of arterial stiffness in an apparently healthy population over 60 years

C. Alecu, R. Gueguen, C. Aubry, P. Salvi, C. Perret-Guillaume, X. Ducrocq, H. Vespignani, A. Benetos

Research output: Contribution to journalArticle

Abstract

Arterial stiffness assessed by the pulse wave velocity (PWV), a non-invasive and reproducible method, predicts cardiovascular morbidity and mortality. The main determinants of arterial stiffness are well established in younger and middle-aged populations, but much less in the elderly. The aim of this study was to describe the determinants of arterial stiffness in elderly apparently healthy subjects. The study included 221 voluntary subjects born before 1944 (mean age 67.4±5.0 years), who had a standard health check-up at the 'Centre de Médecine Préventive' of Nancy. Arterial stiffness was evaluated by measuring the carotid-femoral PWV with the PulsePen automatic device. Clinical and biological parameters were evaluated at the same day. Measurements were valid and analysed in 207 subjects (94 women). Mean PWV was 9.39±2.64m/s. Men showed higher PWV values than women (9.99±2.56 vs 8.66±2.56, P

Original languageEnglish
Pages (from-to)749-756
Number of pages8
JournalJournal of Human Hypertension
Volume20
Issue number10
DOIs
Publication statusPublished - Oct 2006

ASJC Scopus subject areas

  • Internal Medicine

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    Alecu, C., Gueguen, R., Aubry, C., Salvi, P., Perret-Guillaume, C., Ducrocq, X., Vespignani, H., & Benetos, A. (2006). Determinants of arterial stiffness in an apparently healthy population over 60 years. Journal of Human Hypertension, 20(10), 749-756. https://doi.org/10.1038/sj.jhh.1002072