Determinants of invasive vulvar cancer risk: An Italian case-control study

F. Parazzini, C. La Vecchia, S. Garsia, E. Negri, M. Sideri, M. T. Rognoni, M. Origoni

Research output: Contribution to journalArticlepeer-review


Risk factors for vulvar cancer have been evaluated in a case-control study conducted between 1987 and 1990 in northern Italy on 73 women with histologically confirmed invasive vulvar cancer and 572 control subjects in hospital for acute nongynecological, nonneoplastic non-hormone-related conditions. The risk of vulvar cancer was inversely related to education level: with reference to women reporting less than 7 years of schooling, the relative risk estimates were 0.6 and 0.4, respectively, in those reporting 7 to 11 and 12 or more years of schooling (χ1/2 trend = 4.91 P = 0.03). No relationship emerged between number of births and spontaneous or induced abortions. Parous women reporting late first birth tended to be at lower risk (relative risk = 0.5, 95% confidence interval 0.3 to 1.1 for

Original languageEnglish
Pages (from-to)50-55
Number of pages6
JournalGynecologic Oncology
Issue number1
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology


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