Determinants of late outcome after minimally invasive direct coronary artery bypass

Giulio Pompilio, F. Alamanni, P. M. Tartara, C. Antona, M. Porqueddu, F. Veglia, P. Biglioli

Research output: Contribution to journalArticlepeer-review


Aim. Minimally invasive direct coronary artery bypass (MIDCAB) is a reliable method to revascularize the left anterior descending (LAD) coronary artery. However, a more consistent body of knowledge is needed to assess factors influencing long-term outcome. With this study, we retrospectively investigated the long-term determinants of survival and freedom from cardiac morbidity and revascularization in patients who underwent MIDCAB. Methods. From 1997 to 2005, 109 patients underwent MIDCAB. Seventy-five (68.8%) presented isolated LAD disease and 34 (31.2%) multivessel disease. The first 57 patients (53.2%) in the series underwent early postoperative angiographic reinvestigation. All 109 patients were subsequently followed-up at our outpatient clinic. Follow-up (mean 50.7 months, range 3-93) was completed in 100% of cases. Results. No in-hospital deaths occurred; 2 patients (1.8%) experienced perioperative myocardial infarction. At early postoperative angiographic reinvestigation, the anastomotic perfect patency rate was 54/57 (94.7%); survival was 100% and 95.8% at 1 and 5 years, respectively. Overall freedom from repeated revascularization was 95.3% and 88.3% at 1 and 5 years respectively; freedom from LAD revascularization was 95.3% and 91.6% at 1 and 5 years, respectively; cardiac event-free survival was 95.3% and 80.8% at 1 and 5 years respectively. At multivariable analysis (Cox regression), women were found to have a higher risk of repeated LAD revascularization (hazard ratio [HR] 30.24; P

Original languageEnglish
Pages (from-to)207-214
Number of pages8
JournalJournal of Cardiovascular Surgery
Issue number2
Publication statusPublished - Apr 2007


  • Coronary artery bypass
  • Minimally invasive surgical procedures
  • Treatment, outcome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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