Determinants of late outcome after minimally invasive direct coronary artery bypass

Giulio Pompilio, F. Alamanni, P. M. Tartara, C. Antona, M. Porqueddu, F. Veglia, P. Biglioli

Research output: Contribution to journalArticle

Abstract

Aim. Minimally invasive direct coronary artery bypass (MIDCAB) is a reliable method to revascularize the left anterior descending (LAD) coronary artery. However, a more consistent body of knowledge is needed to assess factors influencing long-term outcome. With this study, we retrospectively investigated the long-term determinants of survival and freedom from cardiac morbidity and revascularization in patients who underwent MIDCAB. Methods. From 1997 to 2005, 109 patients underwent MIDCAB. Seventy-five (68.8%) presented isolated LAD disease and 34 (31.2%) multivessel disease. The first 57 patients (53.2%) in the series underwent early postoperative angiographic reinvestigation. All 109 patients were subsequently followed-up at our outpatient clinic. Follow-up (mean 50.7 months, range 3-93) was completed in 100% of cases. Results. No in-hospital deaths occurred; 2 patients (1.8%) experienced perioperative myocardial infarction. At early postoperative angiographic reinvestigation, the anastomotic perfect patency rate was 54/57 (94.7%); survival was 100% and 95.8% at 1 and 5 years, respectively. Overall freedom from repeated revascularization was 95.3% and 88.3% at 1 and 5 years respectively; freedom from LAD revascularization was 95.3% and 91.6% at 1 and 5 years, respectively; cardiac event-free survival was 95.3% and 80.8% at 1 and 5 years respectively. At multivariable analysis (Cox regression), women were found to have a higher risk of repeated LAD revascularization (hazard ratio [HR] 30.24; P

Original languageEnglish
Pages (from-to)207-214
Number of pages8
JournalJournal of Cardiovascular Surgery
Volume48
Issue number2
Publication statusPublished - Apr 2007

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Coronary Artery Bypass
Survival
Ambulatory Care Facilities
Disease-Free Survival
Coronary Vessels
Myocardial Infarction
Regression Analysis
Morbidity

Keywords

  • Coronary artery bypass
  • Minimally invasive surgical procedures
  • Treatment, outcome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Determinants of late outcome after minimally invasive direct coronary artery bypass. / Pompilio, Giulio; Alamanni, F.; Tartara, P. M.; Antona, C.; Porqueddu, M.; Veglia, F.; Biglioli, P.

In: Journal of Cardiovascular Surgery, Vol. 48, No. 2, 04.2007, p. 207-214.

Research output: Contribution to journalArticle

Pompilio, Giulio ; Alamanni, F. ; Tartara, P. M. ; Antona, C. ; Porqueddu, M. ; Veglia, F. ; Biglioli, P. / Determinants of late outcome after minimally invasive direct coronary artery bypass. In: Journal of Cardiovascular Surgery. 2007 ; Vol. 48, No. 2. pp. 207-214.
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abstract = "Aim. Minimally invasive direct coronary artery bypass (MIDCAB) is a reliable method to revascularize the left anterior descending (LAD) coronary artery. However, a more consistent body of knowledge is needed to assess factors influencing long-term outcome. With this study, we retrospectively investigated the long-term determinants of survival and freedom from cardiac morbidity and revascularization in patients who underwent MIDCAB. Methods. From 1997 to 2005, 109 patients underwent MIDCAB. Seventy-five (68.8{\%}) presented isolated LAD disease and 34 (31.2{\%}) multivessel disease. The first 57 patients (53.2{\%}) in the series underwent early postoperative angiographic reinvestigation. All 109 patients were subsequently followed-up at our outpatient clinic. Follow-up (mean 50.7 months, range 3-93) was completed in 100{\%} of cases. Results. No in-hospital deaths occurred; 2 patients (1.8{\%}) experienced perioperative myocardial infarction. At early postoperative angiographic reinvestigation, the anastomotic perfect patency rate was 54/57 (94.7{\%}); survival was 100{\%} and 95.8{\%} at 1 and 5 years, respectively. Overall freedom from repeated revascularization was 95.3{\%} and 88.3{\%} at 1 and 5 years respectively; freedom from LAD revascularization was 95.3{\%} and 91.6{\%} at 1 and 5 years, respectively; cardiac event-free survival was 95.3{\%} and 80.8{\%} at 1 and 5 years respectively. At multivariable analysis (Cox regression), women were found to have a higher risk of repeated LAD revascularization (hazard ratio [HR] 30.24; P",
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AU - Veglia, F.

AU - Biglioli, P.

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