Determinants of long-term clinically detected recurrence rates of deep, ovarian, and pelvic endometriosis

Mauro Busacca, Francesca Chiaffarino, Massimo Candiani, Michele Vignali, Carlo Bertulessi, Giulia Oggioni, Fabio Parazzini

Research output: Contribution to journalArticlepeer-review


Objective: This study was undertaken to analyze the frequency and the determinants of long-term clinically detectable recurrence rate of deep, ovarian, and pelvic endometriosis. Study design: The clinical data of 1106 women with first diagnosis of endometriosis observed between 1979 and 2001 were collected. Results: The 4-year recurrence rate was 24.6%, 17.8%, 30.6% and 23.7%, respectively, for cases of ovarian, pelvic, deep, and ovarian and pelvic endometriosis (P <.05). The recurrence rates decreased in all groups (with the exception of ovarian endometriosis) in the class age 34 years or older, these findings were significant (P <.05). Radicality was associated with lower recurrence rates in all the groups. A pregnancy after diagnosis was associated with a reduced risk of recurrence. Conclusion: The study shows that the recurrence rates of endometriosis were higher in case of deep endometriosis and that the risk factors for recurrence were similar among women with endometriosis at different sites.

Original languageEnglish
Pages (from-to)426-432
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Issue number2
Publication statusPublished - Aug 2006


  • Endometriosis
  • Prognostic factors
  • Risk factors

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynaecology


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