TY - JOUR
T1 - Determinants of oxidative stress related to gender
T2 - Relevance of age and smoking habit
AU - Vassalle, Cristina
AU - Novembrino, Cristina
AU - Maffei, Silvia
AU - Sciarrino, Rosalia
AU - De Giuseppe, Rachele
AU - Vigna, Luisella
AU - De Liso, Federica
AU - Mercuri, Antonella
AU - Bamonti, Fabrizia
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p
AB - Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p
KW - Age
KW - Gender
KW - Menopausal status
KW - Oxidative stress
KW - Smoking habit
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U2 - 10.1515/CCLM.2011.622
DO - 10.1515/CCLM.2011.622
M3 - Article
C2 - 21679134
AN - SCOPUS:80052865473
VL - 49
SP - 1509
EP - 1513
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
SN - 1434-6621
IS - 9
ER -