Determinants of oxidative stress related to gender: Relevance of age and smoking habit

Cristina Vassalle; Cristina Novembrino; Silvia Maffei; Rosalia Sciarrino; Rachele De Giuseppe; Luisella Vigna; Federica De Liso; Antonella Mercuri; Fabrizia Bamonti

doi:10.1515/CCLM.2011.622

Determinants of oxidative stress related to gender: Relevance of age and smoking habit

Cristina Vassalle, Cristina Novembrino, Silvia Maffei, Rosalia Sciarrino, Rachele De Giuseppe, Luisella Vigna, Federica De Liso, Antonella Mercuri, Fabrizia Bamonti

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article

Abstract

Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p

Original language	English
Pages (from-to)	1509-1513
Number of pages	5
Journal	Clinical Chemistry and Laboratory Medicine
Volume	49
Issue number	9
DOIs	https://doi.org/10.1515/CCLM.2011.622
Publication status	Published - Sep 1 2011

Keywords

Age
Gender
Menopausal status
Oxidative stress
Smoking habit

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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10.1515/CCLM.2011.622

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Vassalle, C., Novembrino, C., Maffei, S., Sciarrino, R., De Giuseppe, R., Vigna, L., De Liso, F., Mercuri, A., & Bamonti, F. (2011). Determinants of oxidative stress related to gender: Relevance of age and smoking habit. Clinical Chemistry and Laboratory Medicine, 49(9), 1509-1513. https://doi.org/10.1515/CCLM.2011.622

Determinants of oxidative stress related to gender : Relevance of age and smoking habit. / Vassalle, Cristina; Novembrino, Cristina; Maffei, Silvia; Sciarrino, Rosalia; De Giuseppe, Rachele; Vigna, Luisella ; De Liso, Federica; Mercuri, Antonella; Bamonti, Fabrizia.

In: Clinical Chemistry and Laboratory Medicine, Vol. 49, No. 9, 01.09.2011, p. 1509-1513.

Research output: Contribution to journal › Article

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AU - Vigna, Luisella

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