Abstract
Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p
| Original language | English |
|---|---|
| Pages (from-to) | 1509-1513 |
| Number of pages | 5 |
| Journal | Clinical Chemistry and Laboratory Medicine |
| Volume | 49 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sep 1 2011 |
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Keywords
- Age
- Gender
- Menopausal status
- Oxidative stress
- Smoking habit
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical
Cite this
Determinants of oxidative stress related to gender : Relevance of age and smoking habit. / Vassalle, Cristina; Novembrino, Cristina; Maffei, Silvia; Sciarrino, Rosalia; De Giuseppe, Rachele; Vigna, Luisella; De Liso, Federica; Mercuri, Antonella; Bamonti, Fabrizia.
In: Clinical Chemistry and Laboratory Medicine, Vol. 49, No. 9, 01.09.2011, p. 1509-1513.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Determinants of oxidative stress related to gender
T2 - Relevance of age and smoking habit
AU - Vassalle, Cristina
AU - Novembrino, Cristina
AU - Maffei, Silvia
AU - Sciarrino, Rosalia
AU - De Giuseppe, Rachele
AU - Vigna, Luisella
AU - De Liso, Federica
AU - Mercuri, Antonella
AU - Bamonti, Fabrizia
PY - 2011/9/1
Y1 - 2011/9/1
N2 - Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p
AB - Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p
KW - Age
KW - Gender
KW - Menopausal status
KW - Oxidative stress
KW - Smoking habit
UR - http://www.scopus.com/inward/record.url?scp=80052865473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052865473&partnerID=8YFLogxK
U2 - 10.1515/CCLM.2011.622
DO - 10.1515/CCLM.2011.622
M3 - Article
VL - 49
SP - 1509
EP - 1513
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
SN - 1434-6621
IS - 9
ER -