Determinants of oxidative stress related to gender

Relevance of age and smoking habit

Cristina Vassalle, Cristina Novembrino, Silvia Maffei, Rosalia Sciarrino, Rachele De Giuseppe, Luisella Vigna, Federica De Liso, Antonella Mercuri, Fabrizia Bamonti

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: Magnitude and major causes of oxidative stress may be different between sexes, although limitedly addressed in clinical studies with controversial results. The present study aimed to determine whether any gender-related difference exists concerning oxidative stress in a population of 332 subjects of both sexes, in a wide age range, with and without cigarette smoking habit. Methods: The Oxidative-INDEX was calculated after evaluation of serum hydroperoxides (ROMs) and total antioxidant capacity (OXY) by means of commercial kits (d-ROMs and Oxy-adsorbent Tests, Diacron, Italy) subtracting the OXY standardized variable from the ROMs standardized variable. Results: The Oxidative-INDEX resulted higher in women with respect to men (p

Original languageEnglish
Pages (from-to)1509-1513
Number of pages5
JournalClinical Chemistry and Laboratory Medicine
Volume49
Issue number9
DOIs
Publication statusPublished - Sep 1 2011

Fingerprint

ROM
Oxidative stress
Habits
Oxidative Stress
Smoking
Hydrogen Peroxide
Italy
Antioxidants
Tobacco Products
Adsorbents
Serum
Population
Clinical Studies

Keywords

  • Age
  • Gender
  • Menopausal status
  • Oxidative stress
  • Smoking habit

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

Determinants of oxidative stress related to gender : Relevance of age and smoking habit. / Vassalle, Cristina; Novembrino, Cristina; Maffei, Silvia; Sciarrino, Rosalia; De Giuseppe, Rachele; Vigna, Luisella; De Liso, Federica; Mercuri, Antonella; Bamonti, Fabrizia.

In: Clinical Chemistry and Laboratory Medicine, Vol. 49, No. 9, 01.09.2011, p. 1509-1513.

Research output: Contribution to journalArticle

Vassalle, Cristina ; Novembrino, Cristina ; Maffei, Silvia ; Sciarrino, Rosalia ; De Giuseppe, Rachele ; Vigna, Luisella ; De Liso, Federica ; Mercuri, Antonella ; Bamonti, Fabrizia. / Determinants of oxidative stress related to gender : Relevance of age and smoking habit. In: Clinical Chemistry and Laboratory Medicine. 2011 ; Vol. 49, No. 9. pp. 1509-1513.
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