Determinants of reproductive outcome after abdominal myomectomy for infertility

Silvia Maddalena, Olga De Giorgi, Antonella Pesole, Pier Giorgio Crosignani

Research output: Contribution to journalArticlepeer-review


Objective: To determine the effect of myomectomy as a therapy for infertility and to define the factors that influence reproductive outcome. Design: Retrospective study of a case series. Setting: An academic department specializing in conservative surgery. Patient(s): A total of 138 infertile women who underwent first-line conservative surgical treatment at laparotomy for uterine leiomyomas over an 8-year period. Intervention(s): Data were collected on baseline clinical characteristics, surgical details, and subsequent reproductive history. Main Outcome Measure(s): Cumulative pregnancy rates at 24 months according to selected clinical and fibroid characteristics. Result(s): Pregnancy occurred in 76 women. The 24-month cumulative probability of conception according to the Kaplan-Meier method was 87% in patients 35 years of age. The pregnancy rates in women with and without minor infertility factors in addition to myomas were 56% and 71%, respectively, and those in women with

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalFertility and Sterility
Issue number1
Publication statusPublished - Jul 1999


  • Abortion
  • Conservative surgery
  • Infertility
  • Leiomyomas
  • Uterus

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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