TY - JOUR
T1 - Determinants of SARS-CoV-2 infection in Italian healthcare workers
T2 - a multicenter study
AU - Working Group on SARS-CoV-2 Infection in Italian Healthcare Workers
AU - Boffetta, Paolo
AU - Violante, Francesco
AU - Durando, Paolo
AU - De Palma, Giuseppe
AU - Pira, Enrico
AU - Vimercati, Luigi
AU - Cristaudo, Alfonso
AU - Icardi, Giancarlo
AU - Sala, Emma
AU - Coggiola, Maurizio
AU - Tafuri, Silvio
AU - Gattini, Vittorio
AU - Apostoli, Pietro
AU - Spatari, Giovanna
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2021/3/11
Y1 - 2021/3/11
N2 - Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPEs), and COVID-19-related symptoms. We fitted multivariable logistic regression models to calculate odds ratios and 95% confidence intervals of infection. The prevalence of infection ranged from 3.0 to 22.0%, and was correlated with that of the respective areas. Women were at lower risk of infection compared to men. Fever, cough, dyspnea and malaise were the symptoms most strongly associated with infection, together with anosmia and ageusia. No differences in the risk of infection were detected according to job title, or working in a COVID-19 designated department. Reported contact with a patient inside or outside the workplace was a risk factor. Use of a mask was strongly protective against risk of infection as was use of gloves. The use of a mask by the source of exposure (patient or colleague) had an independent effect in reducing infection risk.
AB - Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPEs), and COVID-19-related symptoms. We fitted multivariable logistic regression models to calculate odds ratios and 95% confidence intervals of infection. The prevalence of infection ranged from 3.0 to 22.0%, and was correlated with that of the respective areas. Women were at lower risk of infection compared to men. Fever, cough, dyspnea and malaise were the symptoms most strongly associated with infection, together with anosmia and ageusia. No differences in the risk of infection were detected according to job title, or working in a COVID-19 designated department. Reported contact with a patient inside or outside the workplace was a risk factor. Use of a mask was strongly protective against risk of infection as was use of gloves. The use of a mask by the source of exposure (patient or colleague) had an independent effect in reducing infection risk.
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U2 - 10.1038/s41598-021-85215-4
DO - 10.1038/s41598-021-85215-4
M3 - Article
C2 - 33707646
AN - SCOPUS:85102804829
VL - 11
SP - 5788
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
IS - 1
ER -