TY - JOUR
T1 - Determinants of short term recurrence rate of endometriosis
AU - Parazzini, Fabio
AU - Bertulessi, Carlo
AU - Pasini, Andrea
AU - Rosati, Maurizio
AU - Di Stefano, Fabio
AU - Shonauer, Sergio
AU - Vicino, Mario
AU - Aguzzoli, Lorenzo
AU - Trossarelli, Gian Franco
AU - Massobrio, Mario
AU - Bracco, Gianluca
AU - Perino, Antonio
AU - Moroni, Simona
AU - Beretta, Paolo
PY - 2005/8/1
Y1 - 2005/8/1
N2 - Objective: To analyse the frequency and the determinants of recurrence rate of clinically detectable endometriosis. Study design: Prospective cohort multicenter study. Eligible for the study were all women observed for the first time during the period January-June 1998 at the participating centres with a laparoscopically confirmed first diagnosis of endometriosis. After diagnosis, patients were treated according to standard care of each centre and desire for pregnancy. The protocol required all women to be followed up at the centre each year for 2 years with a clinical examination, an ultrasound pelvic examination and a CA125 assay, unless pregnancy occurred. Second look laparoscopy was performed on a clinical basis. Results: A total of 311 women (median age 36 years) entered the study. The two-year recurrence rate was 5.7% among cases stage I-II and 14.4% among stage III-IV (χ1
2 adjusted for indication for surgery, p <0.05). The recurrence rates tended to increase with age, being 4.6% among women aged 20-30 and 13.1% among women aged >30, but this finding was not statistically significant. Conclusion: The recurrence rate of clinically detectable endometriosis tends to be higher in older women with advanced stages of the disease and lower in women with infertility.
AB - Objective: To analyse the frequency and the determinants of recurrence rate of clinically detectable endometriosis. Study design: Prospective cohort multicenter study. Eligible for the study were all women observed for the first time during the period January-June 1998 at the participating centres with a laparoscopically confirmed first diagnosis of endometriosis. After diagnosis, patients were treated according to standard care of each centre and desire for pregnancy. The protocol required all women to be followed up at the centre each year for 2 years with a clinical examination, an ultrasound pelvic examination and a CA125 assay, unless pregnancy occurred. Second look laparoscopy was performed on a clinical basis. Results: A total of 311 women (median age 36 years) entered the study. The two-year recurrence rate was 5.7% among cases stage I-II and 14.4% among stage III-IV (χ1
2 adjusted for indication for surgery, p <0.05). The recurrence rates tended to increase with age, being 4.6% among women aged 20-30 and 13.1% among women aged >30, but this finding was not statistically significant. Conclusion: The recurrence rate of clinically detectable endometriosis tends to be higher in older women with advanced stages of the disease and lower in women with infertility.
KW - Endometriosis
KW - Laparoscopy
KW - Recurrence rate
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U2 - 10.1016/j.ejogrb.2004.11.033
DO - 10.1016/j.ejogrb.2004.11.033
M3 - Article
C2 - 16054965
AN - SCOPUS:23044462721
VL - 121
SP - 216
EP - 219
JO - European Journal of Obstetrics, Gynecology and Reproductive Biology
JF - European Journal of Obstetrics, Gynecology and Reproductive Biology
SN - 0028-2243
IS - 2
ER -