@inbook{550a71bb76084889b5ac877ee72b0b33,
title = "Determination of 2-arachidonoylglycerol by μSPE-LC-MS/MS",
abstract = "LC-MS/MS is a powerful analytical technique that provides unequivocal identification and reliable quantification of the analytes, using Selected Reaction Monitoring or Multi Reaction Monitoring acquisition mode. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid, which plays a major role in a wide variety of physiological and pathological processes. Analysis of 2-AG by means of LC-MS/MS allows the detection of very low concentrations in biological samples. Here, we describe how to determine 2-AG levels in tiny samples of tissues and plasma through LC-MS/MS, by using very quick and easy to perform extraction procedures, with reduced solvent consumption.",
keywords = "2-AG, LC-MS/MS, Plasma, Tissue, μSPE",
author = "Natalia Battista and Manuel Sergi",
year = "2016",
doi = "10.1007/978-1-4939-3539-0_3",
language = "English",
volume = "1412",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "19--26",
booktitle = "Methods in Molecular Biology",
}