Determination of epidermal growth factor receptor provides additional prognostic information to measuring tumor angiogenesis in breast carcinoma patients

Noel Weidner, Giampietro Gasparini

Research output: Contribution to journalArticle

Abstract

Recent studies have shown that women with invasive breast carcinoma having high microvessel density (MVD) (a measure of tumor angiogenesis) or epidermal growth factor receptor (EGFR) expression have increased risk for metastasis and/or decreased survival. To determine if MVD and EGFR expression provide additive prognostic information, we analyzed these two prognostic indicators in the primary invasive breast carcinomas from 165 consecutive patients, who were followed for a median of 51 months. Univariate analysis showed a highly significant (p

Original languageEnglish
Pages (from-to)97-107
Number of pages11
JournalBreast Cancer Research and Treatment
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 1994

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Keywords

  • angiogenesis
  • blood vessels
  • breast carcinoma
  • epidermal growth factor receptor
  • metastasis
  • prognostic factors
  • survival

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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