The measurement of serum free light chains (FLC) is thoroughly used in the evaluation of monoclonal gammopathies. However, the FLC assay presents some analytical issues that should be taken into account in the interpretation of results. International guidelines have been formulated for the appropriate use of the FLC assay in clinical practice. The combination of all the available analytical tools, including serum and urine electrophoresis and immunofixation and the FLC assay, provides the best diagnostic sensitivity in different clinical settings.
|Translated title of the contribution||Determination of free light chains in serum: Analytical and clinical aspects|
|Number of pages||4|
|Publication status||Published - Feb 2010|
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical
- Medical Laboratory Technology