La misura delle catene leggere libere delle immunoglobuline nel siero: Aspetti analitici e clinici

Translated title of the contribution: Determination of free light chains in serum: Analytical and clinical aspects

Research output: Contribution to journalArticle

Abstract

The measurement of serum free light chains (FLC) is thoroughly used in the evaluation of monoclonal gammopathies. However, the FLC assay presents some analytical issues that should be taken into account in the interpretation of results. International guidelines have been formulated for the appropriate use of the FLC assay in clinical practice. The combination of all the available analytical tools, including serum and urine electrophoresis and immunofixation and the FLC assay, provides the best diagnostic sensitivity in different clinical settings.

Original languageItalian
Pages (from-to)26-29
Number of pages4
JournalBiochimica Clinica
Volume34
Issue number1
Publication statusPublished - Feb 2010

Fingerprint

Light
Assays
Serum
Paraproteinemias
Electrophoresis
Urine
Guidelines

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical
  • Medical Laboratory Technology

Cite this

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abstract = "The measurement of serum free light chains (FLC) is thoroughly used in the evaluation of monoclonal gammopathies. However, the FLC assay presents some analytical issues that should be taken into account in the interpretation of results. International guidelines have been formulated for the appropriate use of the FLC assay in clinical practice. The combination of all the available analytical tools, including serum and urine electrophoresis and immunofixation and the FLC assay, provides the best diagnostic sensitivity in different clinical settings.",
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